Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable several functions, including RIG-I binding activity; identical protein binding activity; and ubiquitin protein ligase activity. Involved in RIG-I signaling pathway; antiviral innate immune response; and protein polyubiquitination. Predicted to be located in cytoplasmic stress granule. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; heart; and testis. Orthologous to human RNF135 (ring finger protein 135).