Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RGS7
  • Mouse genes Rgs7
  • Rat genes Rgs7
  • Zfish genes rgs7a,rgs7b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rgs7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001965	G-protein alpha-subunit binding	Rgs7	IDA		Rat	PMID:10092682|RGD:69962
Molecular Function	GO:0031681	G-protein beta-subunit binding	RGS7	IPI	UniProtKB:O14775	Human	PMID:19376773
Molecular Function	GO:0031681	G-protein beta-subunit binding	Rgs7	IPI	RGD:620759	Rat	PMID:10840031|RGD:6893668
Molecular Function	GO:0005096	GTPase activator activity	RGS7	IDA		Human	PMID:10521509
Molecular Function	GO:0005515	protein binding	Rgs7	IPI	MGI:MGI:2443409	Mouse	PMID:22689652
Molecular Function	GO:0005515	protein binding	Rgs7	IPI	UniProtKB:Q3UVC4	Mouse	PMID:15897264
Molecular Function	GO:0005515	protein binding	Rgs7	IPI	PR:Q8C419	Mouse	PMID:22689652
Molecular Function	GO:0005515	protein binding	Rgs7	IPI	RGD:628732	Rat	PMID:10092682|RGD:69962
Cellular Component	GO:0005737	cytoplasm	Rgs7	IDA		Rat	PMID:11886441|RGD:13524853
Cellular Component	GO:0005829	cytosol	RGS7	IDA		Human	PMID:10521509
Cellular Component	GO:0005829	cytosol	Rgs7	IDA		Rat	PMID:10840031|RGD:6893668
Cellular Component	GO:0005829	cytosol	Rgs7	IDA		Rat	PMID:14534355|RGD:1601365
Cellular Component	GO:0044292	dendrite terminus	Rgs7	IDA		Mouse	PMID:22689652
Cellular Component	GO:0098978	glutamatergic synapse	Rgs7	IDA		Mouse	PMID:27965545
Cellular Component	GO:0098978	glutamatergic synapse	Rgs7	IDA		Mouse	PMID:24755289
Cellular Component	GO:0098978	glutamatergic synapse	Rgs7	IMP		Mouse	PMID:24755289
Cellular Component	GO:0045121	membrane raft	Rgs7	IDA		Rat	PMID:18248908|RGD:13524856
Cellular Component	GO:0005635	nuclear envelope	Rgs7	IDA		Rat	PMID:11886441|RGD:13524853
Cellular Component	GO:0005634	nucleus	Rgs7	IDA		Mouse	PMID:15897264
Cellular Component	GO:0005886	plasma membrane	Rgs7	IDA		Mouse	PMID:15897264
Cellular Component	GO:0005886	plasma membrane	Rgs7	IDA		Rat	PMID:14534355|RGD:1601365
Cellular Component	GO:0045211	postsynaptic membrane	Rgs7	IDA		Mouse	PMID:27965545
Cellular Component	GO:0098793	presynapse	Rgs7	IDA		Mouse	PMID:27965545
Cellular Component	GO:0032991	protein-containing complex	Rgs7	IDA		Rat	PMID:10840031|RGD:6893668
Biological Process	GO:0007420	brain development	Rgs7	IEP		Rat	PMID:11906535|RGD:13524541
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Rgs7	IDA		Mouse	PMID:15897264
Biological Process	GO:0043547	positive regulation of GTPase activity	RGS7	IDA		Human	PMID:10521509
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	Rgs7	IDA		Rat	PMID:10092682|RGD:69962
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	Rgs7	IDA		Mouse	PMID:22689652
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	Rgs7	IGI	MGI:MGI:2441697	Mouse	PMID:22689652
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	Rgs7	IDA		Rat	PMID:10092682|RGD:69962
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Rgs7	IDA		Mouse	PMID:24755289
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Rgs7	IMP		Mouse	PMID:24755289
Biological Process	GO:0001975	response to amphetamine	Rgs7	IEP		Rat	PMID:26321241|RGD:13524514
Biological Process	GO:0009409	response to cold	Rgs7	IEP		Rat	PMID:18461718|RGD:13524837
Biological Process	GO:0045471	response to ethanol	Rgs7	IEP		Rat	PMID:28736108|RGD:13524510

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern