Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB10
  • Mouse genes Rab10
  • Rat genes Rab10
  • Zfish genes rab10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0098641	cadherin binding involved in cell-cell adhesion	RAB10	HDA		Human	PMID:25468996
Molecular Function	GO:0019003	GDP binding	RAB10	IDA		Human	PMID:20937701
Molecular Function	GO:0051021	GDP-dissociation inhibitor binding	Rab10	IPI	RGD:2676	Rat	PMID:21856246|RGD:8553614
Molecular Function	GO:0005525	GTP binding	RAB10	IDA		Human	PMID:20937701
Molecular Function	GO:0031489	myosin V binding	RAB10	IPI	UniProtKB:Q99104	Human	PMID:22908308
Molecular Function	GO:0031489	myosin V binding	Rab10	IPI	RGD:621347	Rat	PMID:23770993|RGD:11533641
Molecular Function	GO:0005515	protein binding	RAB10	IPI	UniProtKB:Q96CV9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAB10	IPI	UniProtKB:Q14964	Human	PMID:26824392
Molecular Function	GO:0005515	protein binding	RAB10	IPI	UniProtKB:Q5S007	Human	PMID:26824392
Molecular Function	GO:0005515	protein binding	RAB10	IPI	UniProtKB:Q8IYX1	Human	PMID:28067790
Molecular Function	GO:0005515	protein binding	RAB10	IPI	UniProtKB:Q969X0	Human	PMID:29125462
Molecular Function	GO:0005515	protein binding	RAB10	IPI	UniProtKB:Q14964	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	RAB10	IPI	UniProtKB:Q5S007	Human	PMID:31046837
Molecular Function	GO:0005515	protein binding	RAB10	IPI	UniProtKB:Q9ULR3	Human	PMID:31663853
Molecular Function	GO:0005515	protein binding	RAB10	IPI	UniProtKB:Q969X0	Human	PMID:32017888
Molecular Function	GO:0005515	protein binding	Rab10	IPI	UniProtKB:P31150|UniProtKB:P50395	Mouse	MGI:MGI:5448530|PMID:19570034
Molecular Function	GO:0005515	protein binding	Rab10	IPI	UniProtKB:E9QAT4	Mouse	MGI:MGI:5807293|PMID:27354378
Molecular Function	GO:0005515	protein binding	Rab10	IPI	PR:Q99NE5	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rab10	IPI	UniProtKB:P50398	Rat	PMID:21856246|RGD:8553614
Molecular Function	GO:0005515	protein binding	Rab10	IPI	UniProtKB:Q8K4K5	Rat	PMID:21856246|RGD:8553614
Cellular Component	GO:0005912	adherens junction	RAB10	HDA		Human	PMID:25468996
Cellular Component	GO:0005929	cilium	RAB10	IDA		Human	PMID:20576682
Cellular Component	GO:0005929	cilium	Rab10	IDA		Mouse	MGI:MGI:5448525|PMID:20576682
Cellular Component	GO:0005929	cilium	Rab10	IDA		Rat	PMID:20576682|RGD:8553613
Cellular Component	GO:0005789	endoplasmic reticulum membrane	RAB10	IDA		Human	PMID:23263280
Cellular Component	GO:0071782	endoplasmic reticulum tubular network	RAB10	IDA		Human	PMID:23263280
Cellular Component	GO:0005768	endosome	RAB10	IDA		Human	PMID:20576682
Cellular Component	GO:0070382	exocytic vesicle	RAB10	IDA		Human	PMID:18504258
Cellular Component	GO:0070062	extracellular exosome	RAB10	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	RAB10	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	RAB10	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	RAB10	HDA		Human	PMID:21423176
Cellular Component	GO:0005794	Golgi apparatus	RAB10	IDA		Human	PMID:23263280
Cellular Component	GO:0005794	Golgi apparatus	Rab10	IDA		Mouse	PMID:11042173
Cellular Component	GO:0032593	insulin-responsive compartment	RAB10	IDA		Human	PMID:22908308
Cellular Component	GO:0016020	membrane	Rab10	IDA		Rat	PMID:7688123|RGD:734514
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Rab10	IDA		Mouse	MGI:MGI:5807293|PMID:27354378
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Rab10	IDA		Rat	PMID:7688123|RGD:734514
Cellular Component	GO:0005886	plasma membrane	RAB10	IDA		Human	PMID:22908308
Cellular Component	GO:0055037	recycling endosome	RAB10	IDA		Human	PMID:16641372
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab10	EXP		Rat	PMID:20926670|RGD:13432355
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab10	IDA		Rat	PMID:20926670|RGD:13432355
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab10	IMP		Rat	PMID:20926670|RGD:13432355
Cellular Component	GO:0005802	trans-Golgi network	Rab10	IDA		Rat	PMID:7688123|RGD:734514
Biological Process	GO:0019882	antigen processing and presentation	RAB10	IMP		Human	PMID:19717423
Biological Process	GO:0061564	axon development	rab10	IMP	ZFIN:ZDB-MRPHLNO-160310-3	Zfish	PMID:23770993
Biological Process	GO:0061564	axon development	rab10	IMP	ZFIN:ZDB-MRPHLNO-160310-2	Zfish	PMID:23770993
Biological Process	GO:0007409	axonogenesis	Rab10	IMP		Rat	PMID:21856246|RGD:8553614
Biological Process	GO:0071236	cellular response to antibiotic	Rab10	IEP		Rat	PMID:7688123|RGD:734514
Biological Process	GO:0032869	cellular response to insulin stimulus	Rab10	IMP		Mouse	MGI:MGI:5463529|PMID:22908308
Biological Process	GO:0032869	cellular response to insulin stimulus	Rab10	IMP		Mouse	MGI:MGI:5447613|PMID:17403373
Biological Process	GO:0071786	endoplasmic reticulum tubular network organization	RAB10	IMP		Human	PMID:23263280
Biological Process	GO:0071786	endoplasmic reticulum tubular network organization	RAB10	IMP		Human	PMID:24891604
Biological Process	GO:0016197	endosomal transport	RAB10	IMP		Human	PMID:16641372
Biological Process	GO:0045200	establishment of neuroblast polarity	Rab10	IMP		Rat	PMID:21856246|RGD:8553614
Biological Process	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane	RAB10	IMP		Human	PMID:23263280
Biological Process	GO:0090150	establishment of protein localization to membrane	RAB10	IMP		Human	PMID:24006491
Biological Process	GO:0006893	Golgi to plasma membrane transport	Rab10	IMP		Rat	PMID:21856246|RGD:8553614
Biological Process	GO:0072659	protein localization to plasma membrane	Rab10	IMP		Mouse	MGI:MGI:5807293|PMID:27354378
Biological Process	GO:0072659	protein localization to plasma membrane	Rab10	IMP		Mouse	MGI:MGI:5463529|PMID:22908308
Biological Process	GO:0072659	protein localization to plasma membrane	Rab10	IMP		Mouse	MGI:MGI:5447613|PMID:17403373
Biological Process	GO:0045055	regulated exocytosis	RAB10	IMP		Human	PMID:2732579
Biological Process	GO:0016192	vesicle-mediated transport	Rab10	IMP		Mouse	MGI:MGI:5463529|PMID:22908308

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern