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Rab10 Gene Detail
Summary
  • Symbol
    Rab10
  • Name
    RAB10, member RAS oncogene family
  • Feature Type
    protein coding gene
  • IDs
    MGI:105066
    NCBI Gene: 19325
Location & Maps
more
  • Sequence Map
    Chr12:3247430-3309969 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      62540 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    RAB10, RAB10, member RAS oncogene family
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RAB10, RAB10, member RAS oncogene family
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 10890
    neXtProt AC: NX_P61026

  • Chr Location
    2p23.3; chr2:26033860-26137454 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020671 Ensembl Gene Model | MGI Sequence Detail 62540 C57BL/6J ±  kb
transcript ENSMUST00000021001 Ensembl | MGI Sequence Detail 3511 Not Applicable  
polypeptide ENSMUSP00000021001 Ensembl | MGI Sequence Detail 200 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    199 from dbSNP Build 137
  • RFLP
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013578 ras-related protein Rab-10
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR003579 Small GTPase superfamily, Rab type
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
less
  • All nucleic 27
    cDNA 27

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-32105, MGI:2145003
References
more
  • Summaries
    All 39
    Gene Ontology 11
    Phenotypes 6
  • Earliest
    J:30578 Barbosa MD, et al., The Rab protein family: genetic mapping of six Rab genes in the mouse. Genomics. 1995 Dec 10;30(3):439-44
  • Latest
    J:211898 Sato T, et al., Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis. J Cell Sci. 2014 Jan 15;127(Pt 2):422-31

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory