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Rab10
Gene Detail
 Symbol
Name
ID
Rab10
RAB10, member RAS oncogene family
MGI:105066
Feature Type protein coding gene
Genetic Map
Chromosome 12
1.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:3247430-3309969 bp, - strand
From Ensembl annotation of GRCm38

  62540 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41111  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab10

Human
homologs
Human Homolog RAB10, RAB10, member RAS oncogene family
NCBI Gene ID 10890
neXtProt AC  NX_P61026
Human Chr (Location)  2p23.3; chr2:26033860-26137454 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(23) : Gene trapped(21) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rab10 interacts with 366 markers (Mir7-1, Mir10b, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (43 annotations)
Process antigen processing and presentation, axonogenesis, ...
Component cell, cell projection, ...
Function GDP binding, GTPase activity, ...
External Resources: FuncBase
Expression
cDNA source data(24)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(27) cDNA(27)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000020671 (Evidence)
Entrez Gene19325 (Evidence)
DFCITC1573388, TC1605208
DoTSDT.101405537, DT.87072967
NIA Mouse Gene IndexU033752
Consensus CDS ProjectCCDS25782.1
International Mouse Knockout Project StatusRab10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020671 Ensembl Gene Model | MGI Sequence Detail 62540 C57BL/6J ±  kb
transcript ENSMUST00000021001 Ensembl | MGI Sequence Detail 3511 Not Applicable 
polypeptide ENSMUSP00000021001 Ensembl | MGI Sequence Detail 200 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(2) UniProt(3)
Polymorphisms RFLP(1) : SNPs within 2kb(199 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013578 ras-related protein Rab-10
References (Earliest) J:30578 Barbosa MD, et al., The Rab protein family: genetic mapping of six Rab genes in the mouse. Genomics. 1995 Dec 10;30(3):439-44
(Latest) J:191891 Chen Y, et al., Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes. J Cell Biol. 2012 Aug 20;198(4):545-60
All references(42)
Other
accession IDs
MGD-MRK-32105, MGI:2145003

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory