Rab10
Gene Detail

Symbol Name ID

Rab10 RAB10, member RAS oncogene family MGI:105066

Feature Type

protein coding gene

Genetic Map

Chromosome 12

1.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr12:3247430-3309969 bp, - strand From Ensembl annotation of GRCm38   62540 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:41111  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab10

Human homologs

Human Homolog		RAB10, RAB10, member RAS oncogene family
NCBI Gene ID		10890
neXtProt AC		NX_P61026
Human Chr (Location)		2p23.3; chr2:26256729-26360323 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(23) : Targeted(2) Gene trapped(21)

Gene Ontology (GO) classifications

All GO classifications: (39 annotations)

Process	axonogenesis, cellular response to insulin stimulus, ...
Component	cell projection, cytoplasmic vesicle, ...
Function	GDP binding, GTPase activity, ...

External Resources: FuncBase

Expression

cDNA source data(24)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(27) cDNA(27)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000020671 (Evidence)
Entrez Gene	19325 (Evidence)
DFCI	TC1573388, TC1605208
DoTS	DT.101405537, DT.87072967
NIA Mouse Gene Index	U033752
Consensus CDS Project	CCDS25782.1
International Mouse Knockout Project Status	Rab10

Sequences

Length	Strain/Species
genomic	ENSMUSG00000020671	Ensembl Gene Model | MGI Sequence Detail	62540	C57BL/6J
transcript	ENSMUST00000021001	Ensembl | MGI Sequence Detail	3511	Not Applicable
polypeptide	ENSMUSP00000021001	Ensembl | MGI Sequence Detail	200	Not Applicable

All sequences(56) RefSeq(2) UniProt(3)

Polymorphisms

RFLP(1) : SNPs(101 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR003579	Small GTPase superfamily, Rab type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013578	ras-related protein Rab-10

References

(Earliest) J:30578 Barbosa MD, et al., The Rab protein family: genetic mapping of six Rab genes in the mouse. Genomics. 1995 Dec 10;30(3):439-44
(Latest) J:191891 Chen Y, et al., Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes. J Cell Biol. 2012 Aug 20;198(4):545-60
All references(42)

Other accession IDs

MGD-MRK-32105, MGI:2145003