Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PYGO2
  • Mouse genes Pygo2
  • Rat genes Pygo2
  • Zfish genes pygo2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pygo2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Pygo2	IDA		Mouse	PMID:23637336
Molecular Function	GO:0035034	histone acetyltransferase regulator activity	Pygo2	IMP	MGI:MGI:5518423	Mouse	PMID:23637336
Molecular Function	GO:0042393	histone binding	Pygo2	IDA		Mouse	PMID:19487454
Molecular Function	GO:0042393	histone binding	Pygo2	IMP	MGI:MGI:5518423	Mouse	PMID:23637336
Molecular Function	GO:0005515	protein binding	PYGO2	IPI	UniProtKB:O00512	Human	PMID:17113272
Molecular Function	GO:0005515	protein binding	PYGO2	IPI	UniProtKB:O00512	Human	PMID:21399610
Molecular Function	GO:0005515	protein binding	PYGO2	IPI	UniProtKB:O00512	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	PYGO2	IPI	UniProtKB:Q9UPU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pygo2	IPI	PR:P61965	Mouse	PMID:19487454
Cellular Component	GO:1990907	beta-catenin-TCF complex	PYGO2	IDA		Human	PMID:28296634
Cellular Component	GO:0005634	nucleus	Pygo2	IDA		Mouse	PMID:23637336
Cellular Component	GO:0005634	nucleus	Pygo2	IDA		Mouse	PMID:17425782
Biological Process	GO:0048856	anatomical structure development	Pygo2	IGI	MGI:MGI:1919385	Mouse	PMID:17425782
Biological Process	GO:0048856	anatomical structure development	Pygo2	IMP	MGI:MGI:3712856	Mouse	PMID:17425782
Biological Process	GO:0007420	brain development	Pygo2	IMP	MGI:MGI:3712856	Mouse	PMID:17425782
Biological Process	GO:0060070	canonical Wnt signaling pathway	Pygo2	IMP	MGI:MGI:3712856	Mouse	PMID:17425782
Biological Process	GO:0060070	canonical Wnt signaling pathway	Pygo2	IGI	MGI:MGI:1919385	Mouse	PMID:17425782
Biological Process	GO:0060070	canonical Wnt signaling pathway	Pygo2	IMP	MGI:MGI:3711738	Mouse	PMID:19487454
Biological Process	GO:0048589	developmental growth	Pygo2	IMP	MGI:MGI:3712856	Mouse	PMID:17425782
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	pygo2	IGI	ZFIN:ZDB-GENO-200319-14	Zfish	PMID:30366904
Biological Process	GO:0001822	kidney development	Pygo2	IGI	MGI:MGI:1919385	Mouse	PMID:17425782
Biological Process	GO:0002088	lens development in camera-type eye	Pygo2	IMP	MGI:MGI:3712856	Mouse	PMID:17425782
Biological Process	GO:0030879	mammary gland development	Pygo2	IMP	MGI:MGI:3711738	Mouse	PMID:19487454
Biological Process	GO:0035563	positive regulation of chromatin binding	Pygo2	IMP	MGI:MGI:5518423	Mouse	PMID:23637336
Biological Process	GO:1905066	regulation of canonical Wnt signaling pathway involved in heart development	pygo2	IGI	ZFIN:ZDB-GENO-200319-14	Zfish	PMID:30366904
Biological Process	GO:0033599	regulation of mammary gland epithelial cell proliferation	Pygo2	IMP	MGI:MGI:3711738	Mouse	PMID:19487454
Biological Process	GO:0060021	roof of mouth development	Pygo2	IMP	MGI:MGI:3712856	Mouse	PMID:17425782
Biological Process	GO:0007286	spermatid development	Pygo2	IGI	MGI:MGI:1919385	Mouse	PMID:23637336
Biological Process	GO:0007289	spermatid nucleus differentiation	Pygo2	IGI	MGI:MGI:1919385	Mouse	PMID:23637336

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern