Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPRR
  • Mouse genes Ptprr
  • Rat genes Ptprr
  • Zfish genes ptprr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptprr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PTPRR	IPI	UniProtKB:P28482	Human	PMID:10601328
Molecular Function	GO:0005515	protein binding	PTPRR	IPI	UniProtKB:Q16539	Human	PMID:10601328
Molecular Function	GO:0005515	protein binding	PTPRR	IPI	UniProtKB:P28482	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	PTPRR	IPI	UniProtKB:P04626	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	PTPRR	IPI	UniProtKB:P06213	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	Ptprr	IPI	UniProtKB:P27361	Mouse	MGI:MGI:5508300|PMID:10066421
Molecular Function	GO:0005515	protein binding	Ptprr	IPI	UniProtKB:P27361|UniProtKB:P63085	Mouse	MGI:MGI:5508299|PMID:10419510
Molecular Function	GO:0005515	protein binding	Ptprr	IPI	UniProtKB:P63085	Mouse	MGI:MGI:5508262|PMID:16148006
Molecular Function	GO:0005515	protein binding	Ptprr	IPI	UniProtKB:Q9WUD9	Rat	PMID:12526090|RGD:8553513
Molecular Function	GO:0019901	protein kinase binding	Ptprr	IDA		Mouse	MGI:MGI:3687779|PMID:10601328
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptprr	IDA		Mouse	PMID:7832766
Cellular Component	GO:0030054	cell junction	PTPRR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	PTPRR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	PTPRR	HDA		Human	PMID:22664934
Cellular Component	GO:0005886	plasma membrane	PTPRR	IDA		Human	GO_REF:0000052
Biological Process	GO:0038128	ERBB2 signaling pathway	PTPRR	IMP		Human	PMID:21724833
Biological Process	GO:0001701	in utero embryonic development	PTPRR	IEP		Human	PMID:10601328
Biological Process	GO:0010633	negative regulation of epithelial cell migration	PTPRR	IMP		Human	PMID:21724833
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	PTPRR	IMP		Human	PMID:21724833
Biological Process	GO:0007399	nervous system development	Ptprr	IEP		Rat	PMID:7814416|RGD:729713
Biological Process	GO:0030182	neuron differentiation	Ptprr	IEP		Rat	PMID:7814416|RGD:729713
Biological Process	GO:0006470	protein dephosphorylation	Ptprr	IDA		Mouse	PMID:7832766

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern