About   Help   FAQ
Gene Ontology Browser
Term Detail
GO term:protein tyrosine phosphatase activity
Synonym: phosphoprotein phosphatase (phosphotyrosine) activity
Synonym: phosphotyrosine histone phosphatase activity
Synonym: phosphotyrosine phosphatase activity
Synonym: [phosphotyrosine]protein phosphatase activity
Synonym: phosphotyrosine protein phosphatase activity
Synonym: phosphotyrosylprotein phosphatase activity
Synonym: PPT-phosphatase activity
Synonym: protein phosphotyrosine phosphatase activity
Synonym: protein-tyrosine-phosphatase activity
Synonym: protein-tyrosine-phosphate phosphohydrolase activity
Synonym: PTPase activity
Synonym: PTP-phosphatase activity
Synonym: tyrosine O-phosphate phosphatase activity
Synonym: tyrosylprotein phosphatase activity
GO id:GO:0004725
Definition:Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship

obsolete Gene_Ontology
                is-acatalytic activity
                        is-ahydrolase activity
                                is-ahydrolase activity, acting on ester bonds
                                        is-aphosphoric ester hydrolase activity
                                                is-aphosphatase activity
                                                        is-aphosphoprotein phosphatase activity
                                                                is-aMAP kinase phosphatase activity +
                                                                is-aprotein arginine phosphatase activity
                                                                is-aprotein serine/threonine phosphatase activity +
                                                                is-aprotein tyrosine phosphatase activity [GO:0004725] (95 genes, 121 annotations)
                                                                        is-aMAP kinase threonine phosphatase activity
                                                                        is-aMAP kinase tyrosine phosphatase activity
                                                                        is-anon-membrane spanning protein tyrosine phosphatase activity
                                                                        is-aprenylated protein tyrosine phosphatase activity
                                                                        is-aprotein tyrosine phosphatase activity, metal-dependent
                                                                        is-aprotein tyrosine phosphatase activity, via thiol-phosphate intermediate
                                                                        is-areceptor signaling protein tyrosine phosphatase activity
                                                                        is-atransmembrane receptor protein tyrosine phosphatase activity
                                                                is-aprotein tyrosine/serine/threonine phosphatase activity +
                                                                is-aprotein tyrosine/threonine phosphatase activity
                                                                is-atransmembrane receptor protein phosphatase activity +

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.02
The Jackson Laboratory