Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPRE
  • Mouse genes Ptpre
  • Rat genes Ptpre
  • Zfish genes ptprea,ptpreb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptpre

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Ptpre	IPI	PR:P49446	Mouse	PMID:12861030
Molecular Function	GO:0005515	protein binding	PTPRE	IPI	UniProtKB:P62993	Human	PMID:10980613
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptpre	IDA		Mouse	PMID:12861030
Cellular Component	GO:0005737	cytoplasm	PTPRE	IDA		Human	PMID:10980613
Cellular Component	GO:0005737	cytoplasm	Ptpre	IDA		Mouse	MGI:MGI:3772995|PMID:18006633
Cellular Component	GO:0005634	nucleus	PTPRE	IDA		Human	PMID:10980613
Cellular Component	GO:0005886	plasma membrane	PTPRE	IDA		Human	PMID:10980613
Cellular Component	GO:0005886	plasma membrane	Ptpre	IDA		Mouse	MGI:MGI:3772995|PMID:18006633
Biological Process	GO:0060027	convergent extension involved in gastrulation	ptpreb	IGI	ZFIN:ZDB-MRPHLNO-100714-3,ZFIN:ZDB-MRPHLNO-100714-4	Zfish	PMID:20188722
Biological Process	GO:0060027	convergent extension involved in gastrulation	ptpreb	IGI	ZFIN:ZDB-MRPHLNO-041217-10,ZFIN:ZDB-MRPHLNO-100714-3,ZFIN:ZDB-MRPHLNO-100714-4	Zfish	PMID:20188722
Biological Process	GO:0060027	convergent extension involved in gastrulation	ptprea	IGI	ZFIN:ZDB-MRPHLNO-041217-10,ZFIN:ZDB-MRPHLNO-100714-3,ZFIN:ZDB-MRPHLNO-100714-4	Zfish	PMID:20188722
Biological Process	GO:0060027	convergent extension involved in gastrulation	ptprea	IGI	ZFIN:ZDB-MRPHLNO-100714-3,ZFIN:ZDB-MRPHLNO-100714-4	Zfish	PMID:20188722
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	Ptpre	IDA		Mouse	MGI:MGI:3772995|PMID:18006633
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	Ptpre	IDA		Rat	PMID:15738637|RGD:8553759
Biological Process	GO:0033003	regulation of mast cell activation	Ptpre	IMP		Mouse	MGI:MGI:4412219|PMID:19508371
Biological Process	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	Ptpre	IDA		Mouse	PMID:12861030

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern