Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ptpn5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PTPN5
- Mouse genes Ptpn5
- Rat genes Ptpn5
- Zfish genes ptpn5
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptpn5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035254	glutamate receptor binding	Ptpn5	IPI	RGD:2738	Rat	PMID:19625523\|RGD:9835004
Molecular Function	GO:0042802	identical protein binding	Ptpn5	IPI	RGD:3448	Rat	PMID:27103516\|RGD:11574252
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	Ptpn5	IPI	RGD:70496	Rat	PMID:19625523\|RGD:9835004
Molecular Function	GO:0051019	mitogen-activated protein kinase binding	Ptpn5	IPI	RGD:70500	Rat	PMID:19625523\|RGD:9835004
Molecular Function	GO:0001784	phosphotyrosine residue binding	PTPN5	IDA		Human	PMID:16441242
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:Q07325	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:Q9BSA0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:Q9NW97	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:Q9UEU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:Q9UEU0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:O14569	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:O75355-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:P78383	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:Q5SNT2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:Q6UXB4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PTPN5	IPI	UniProtKB:Q9NX47	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ptpn5	IPI	UniProtKB:Q16539-1	Mouse	MGI:MGI:5916414\|PMID:23932588
Molecular Function	GO:0019901	protein kinase binding	Ptpn5	IPI	RGD:2641	Rat	PMID:19625523\|RGD:9835004
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptpn5	IMP		Mouse	PMID:16025111
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptpn5	IDA		Rat	PMID:19625523\|RGD:9835004
Cellular Component	GO:0030424	axon	Ptpn5	IDA		Rat	PMID:7869116\|RGD:9835015
Cellular Component	GO:0005829	cytosol	Ptpn5	IDA		Rat	PMID:8331384\|RGD:9835009
Cellular Component	GO:0005783	endoplasmic reticulum	Ptpn5	IDA		Rat	PMID:8987810\|RGD:10044038
Cellular Component	GO:0016020	membrane	Ptpn5	IDA		Rat	PMID:7869116\|RGD:9835015
Cellular Component	GO:0043025	neuronal cell body	Ptpn5	IDA		Rat	PMID:8331384\|RGD:9835009
Cellular Component	GO:0043204	perikaryon	Ptpn5	IDA		Rat	PMID:10101226\|RGD:9835028
Cellular Component	GO:1990635	proximal dendrite	Ptpn5	IDA		Rat	PMID:8331384\|RGD:9835009
Cellular Component	GO:0097060	synaptic membrane	Ptpn5	IDA		Rat	PMID:27103516\|RGD:11574252
Cellular Component	GO:0008021	synaptic vesicle	Ptpn5	IDA		Rat	PMID:27103516\|RGD:11574252
Biological Process	GO:0007568	aging	Ptpn5	IEP		Rat	PMID:27103516\|RGD:11574252
Biological Process	GO:0035640	exploration behavior	Ptpn5	IDA		Rat	PMID:17008368\|RGD:9835026
Biological Process	GO:0043407	negative regulation of MAP kinase activity	Ptpn5	IDA		Rat	PMID:9857190\|RGD:10044039
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	Ptpn5	IDA		Rat	PMID:19625523\|RGD:9835004
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	Ptpn5	IDA		Rat	PMID:9857190\|RGD:10044039
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	Ptpn5	IMP		Rat	PMID:19026408\|RGD:9835020
Biological Process	GO:1901216	positive regulation of neuron death	Ptpn5	IMP		Rat	PMID:19625523\|RGD:9835004
Biological Process	GO:0010976	positive regulation of neuron projection development	Ptpn5	IMP		Rat	PMID:10101226\|RGD:9835028
Biological Process	GO:0042307	positive regulation of protein import into nucleus	Ptpn5	IMP		Rat	PMID:12483215\|RGD:9835024
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Ptpn5	IMP		Rat	PMID:19625523\|RGD:9835004
Biological Process	GO:1903955	positive regulation of protein targeting to mitochondrion	Ptpn5	IMP		Rat	PMID:19625523\|RGD:9835004
Biological Process	GO:0002092	positive regulation of receptor internalization	Ptpn5	IMP		Rat	PMID:19625523\|RGD:9835004
Biological Process	GO:2001025	positive regulation of response to drug	Ptpn5	IMP		Rat	PMID:19026408\|RGD:9835020
Biological Process	GO:0006470	protein dephosphorylation	Ptpn5	IMP		Mouse	PMID:16025111
Biological Process	GO:1903492	response to acetylsalicylate	Ptpn5	IEP		Rat	PMID:14563943\|RGD:10044035
Biological Process	GO:0001975	response to amphetamine	Ptpn5	IEP		Rat	PMID:23711322\|RGD:9835030
Biological Process	GO:0035902	response to immobilization stress	Ptpn5	IDA		Rat	PMID:17008368\|RGD:9835026
Biological Process	GO:0009410	response to xenobiotic stimulus	Ptpn5	IEP		Rat	PMID:17623046\|RGD:9835025

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.