Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRMT2
  • Mouse genes Prmt2
  • Rat genes Prmt2
  • Zfish genes prmt2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prmt2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	Prmt2	IPI	UniProtKB:P26233	Mouse	MGI:MGI:5448523|PMID:20708585
Molecular Function	GO:0140938	histone H3 methyltransferase activity	Prmt2	IDA		Mouse	MGI:MGI:5448523|PMID:20708585
Molecular Function	GO:0042054	histone methyltransferase activity	PRMT2	IDA		Human	PMID:19405910
Molecular Function	GO:0042802	identical protein binding	prmt2	IPI	ZFIN:ZDB-GENE-041104-1	Zfish	PMID:27879050
Molecular Function	GO:0050681	nuclear androgen receptor binding	PRMT2	IPI	UniProtKB:P10275	Human	PMID:17587566
Molecular Function	GO:0030331	nuclear estrogen receptor binding	PRMT2	IPI	UniProtKB:P03372	Human	PMID:12039952
Molecular Function	GO:0030331	nuclear estrogen receptor binding	PRMT2	IPI	UniProtKB:Q92731	Human	PMID:12039952
Molecular Function	GO:0030331	nuclear estrogen receptor binding	PRMT2	IDA		Human	PMID:17587566
Molecular Function	GO:0033142	nuclear progesterone receptor binding	PRMT2	IPI	UniProtKB:P06401	Human	PMID:12039952
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	PRMT2	IPI	UniProtKB:P10276	Human	PMID:12039952
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	PRMT2	IPI	UniProtKB:P19793	Human	PMID:12039952
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	PRMT2	IPI	UniProtKB:P10828	Human	PMID:12039952
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	PRMT2	IPI	UniProtKB:P37231	Human	PMID:12039952
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:Q9BUJ2	Human	PMID:11513728
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:P03372	Human	PMID:12039952
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:Q14686	Human	PMID:12039952
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:Q15788	Human	PMID:12039952
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:P06400	Human	PMID:16616919
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:P25963	Human	PMID:16648481
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:Q9NR22	Human	PMID:17925405
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:P03372	Human	PMID:22093364
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:Q15637	Human	PMID:26420826
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:Q13191	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:Q9NTZ6	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	PRMT2	IPI	UniProtKB:P42858	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Prmt2	IPI	UniProtKB:P13405	Mouse	MGI:MGI:3653799|PMID:16616919
Molecular Function	GO:0042803	protein homodimerization activity	PRMT2	IPI	UniProtKB:P55345	Human	PMID:12039952
Molecular Function	GO:0016274	protein-arginine N-methyltransferase activity	Prmt2	IMP		Mouse	MGI:MGI:5297664|PMID:20798359
Molecular Function	GO:0044877	protein-containing complex binding	Prmt2	IPI	ComplexPortal:CPX-160	Mouse	MGI:MGI:3653799|PMID:16616919
Molecular Function	GO:0003713	transcription coactivator activity	PRMT2	IDA		Human	PMID:12039952
Cellular Component	GO:0005737	cytoplasm	PRMT2	IDA		Human	PMID:11513728
Cellular Component	GO:0005737	cytoplasm	PRMT2	IDA		Human	PMID:17587566
Cellular Component	GO:0005829	cytosol	PRMT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	PRMT2	IDA		Human	PMID:17587566
Cellular Component	GO:0005654	nucleoplasm	PRMT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PRMT2	IDA		Human	PMID:11513728
Cellular Component	GO:0005634	nucleus	PRMT2	IDA		Human	PMID:17587566
Biological Process	GO:0048588	developmental cell growth	Prmt2	IMP		Mouse	MGI:MGI:5297664|PMID:20798359
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Prmt2	IMP		Mouse	MGI:MGI:3653799|PMID:16616919
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	PRMT2	IDA		Human	PMID:16648481
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Prmt2	IDA		Mouse	MGI:MGI:3653799|PMID:16616919
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	Prmt2	IMP		Mouse	MGI:MGI:3653799|PMID:16616919
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	PRMT2	IDA		Human	PMID:16648481
Biological Process	GO:0043065	positive regulation of apoptotic process	PRMT2	IGI	UniProtKB:Q9R144	Human	PMID:16648481
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	PRMT2	IDA		Human	PMID:12039952
Biological Process	GO:0060765	regulation of androgen receptor signaling pathway	PRMT2	IDA		Human	PMID:17587566
Biological Process	GO:0001666	response to hypoxia	Prmt2	IDA		Mouse	MGI:MGI:3762283|PMID:16690984

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern