Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PREX2
  • Mouse genes Prex2
  • Rat genes Prex2
  • Zfish genes prex2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prex2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	PREX2	IDA		Human	PMID:15304343
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	PREX2	IDA		Human	PMID:15304343
Cellular Component	GO:0005886	plasma membrane	Prex2	IDA		Mouse	PMID:24367090
Biological Process	GO:0008344	adult locomotory behavior	Prex2	IMP	MGI:MGI:3783295	Mouse	PMID:18334636
Biological Process	GO:0048813	dendrite morphogenesis	Prex2	IMP	MGI:MGI:3783295	Mouse	PMID:18334636
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	PREX2	IDA		Human	PMID:15304343
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	Prex2	IMP	MGI:MGI:3856561	Mouse	PMID:24367090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern