| GO term: | phosphatidylinositol 3-kinase cascade |
| Synonym: | phosphoinositide 3-kinase cascade |
| Synonym: | PI3K cascade |
| Synonym: | PI 3-kinase cascade |
| GO id: | GO:0014065 |
| Definition: | A series of reactions, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). PI3K cascades lie downstream of many cell surface receptor linked signaling pathways and regulate numerous cellular functions. |
| Number of paths to term: | 10 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processbiological regulationregulation of biological processregulation of cellular processsignal transductionintracellular signal transductioninositol lipid-mediated signalingphosphatidylinositol-mediated signalingphosphatidylinositol 3-kinase cascade [GO:0014065] (71 genes, 78 annotations)negative regulation of phosphatidylinositol 3-kinase cascadepositive regulation of phosphatidylinositol 3-kinase cascaderegulation of phosphatidylinositol 3-kinase cascade +biological_processcellular processregulation of cellular processsignal transductionintracellular signal transductioninositol lipid-mediated signalingphosphatidylinositol-mediated signalingphosphatidylinositol 3-kinase cascade [GO:0014065] (71 genes, 78 annotations)negative regulation of phosphatidylinositol 3-kinase cascadepositive regulation of phosphatidylinositol 3-kinase cascaderegulation of phosphatidylinositol 3-kinase cascade +biological_processcellular processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductioninositol lipid-mediated signalingphosphatidylinositol-mediated signalingphosphatidylinositol 3-kinase cascade [GO:0014065] (71 genes, 78 annotations)negative regulation of phosphatidylinositol 3-kinase cascadepositive regulation of phosphatidylinositol 3-kinase cascaderegulation of phosphatidylinositol 3-kinase cascade +biological_processcellular processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductioninositol lipid-mediated signalingphosphatidylinositol-mediated signalingphosphatidylinositol 3-kinase cascade [GO:0014065] (71 genes, 78 annotations)negative regulation of phosphatidylinositol 3-kinase cascadepositive regulation of phosphatidylinositol 3-kinase cascaderegulation of phosphatidylinositol 3-kinase cascade +biological_processregulation of biological processregulation of cellular processsignal transductionintracellular signal transductioninositol lipid-mediated signalingphosphatidylinositol-mediated signalingphosphatidylinositol 3-kinase cascade [GO:0014065] (71 genes, 78 annotations)negative regulation of phosphatidylinositol 3-kinase cascadepositive regulation of phosphatidylinositol 3-kinase cascaderegulation of phosphatidylinositol 3-kinase cascade +biological_processresponse to stimuluscellular response to stimulussignal transductionintracellular signal transductioninositol lipid-mediated signalingphosphatidylinositol-mediated signalingphosphatidylinositol 3-kinase cascade [GO:0014065] (71 genes, 78 annotations)negative regulation of phosphatidylinositol 3-kinase cascadepositive regulation of phosphatidylinositol 3-kinase cascaderegulation of phosphatidylinositol 3-kinase cascade +biological_processsignalingsingle organism signalingsignal transductionintracellular signal transductioninositol lipid-mediated signalingphosphatidylinositol-mediated signalingphosphatidylinositol 3-kinase cascade [GO:0014065] (71 genes, 78 annotations)negative regulation of phosphatidylinositol 3-kinase cascadepositive regulation of phosphatidylinositol 3-kinase cascaderegulation of phosphatidylinositol 3-kinase cascade +biological_processsingle-organism processsingle organism signalingsignal transductionintracellular signal transductioninositol lipid-mediated signalingphosphatidylinositol-mediated signalingphosphatidylinositol 3-kinase cascade [GO:0014065] (71 genes, 78 annotations)negative regulation of phosphatidylinositol 3-kinase cascadepositive regulation of phosphatidylinositol 3-kinase cascaderegulation of phosphatidylinositol 3-kinase cascade +biological_processsingle-organism processsingle-organism cellular processcell communicationsignal transductionintracellular signal transductioninositol lipid-mediated signalingphosphatidylinositol-mediated signalingphosphatidylinositol 3-kinase cascade [GO:0014065] (71 genes, 78 annotations)negative regulation of phosphatidylinositol 3-kinase cascadepositive regulation of phosphatidylinositol 3-kinase cascaderegulation of phosphatidylinositol 3-kinase cascade +biological_processsingle-organism processsingle-organism cellular processcellular response to stimulussignal transductionintracellular signal transductioninositol lipid-mediated signalingphosphatidylinositol-mediated signalingphosphatidylinositol 3-kinase cascade [GO:0014065] (71 genes, 78 annotations)negative regulation of phosphatidylinositol 3-kinase cascadepositive regulation of phosphatidylinositol 3-kinase cascaderegulation of phosphatidylinositol 3-kinase cascade +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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