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Gene Ontology Browser
Term Detail
GO term:phosphatidylinositol 3-kinase signaling
Synonym: phosphatidylinositol 3-kinase cascade
Synonym: phosphatidylinositol 3-kinase signal transduction
Synonym: phosphoinositide 3-kinase cascade
Synonym: PI3K cascade
Synonym: PI 3-kinase cascade
Synonym: PI3K signaling
Synonym: PI3K signal transduction
GO id:GO:0014065
Definition:A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-aintracellular signal transduction
                                                        is-ainositol lipid-mediated signaling
                                                                is-aphosphatidylinositol-mediated signaling
                                                                        is-aphosphatidylinositol 3-kinase signaling [GO:0014065] (83 genes, 93 annotations)
                                                                                negatively-regulatesnegative regulation of phosphatidylinositol 3-kinase signaling
                                                                                positively-regulatespositive regulation of phosphatidylinositol 3-kinase signaling
                                                                                regulatesregulation of phosphatidylinositol 3-kinase signaling +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-ainositol lipid-mediated signaling
                                                        is-aphosphatidylinositol-mediated signaling
                                                                is-aphosphatidylinositol 3-kinase signaling [GO:0014065] (83 genes, 93 annotations)
                                                                        negatively-regulatesnegative regulation of phosphatidylinositol 3-kinase signaling
                                                                        positively-regulatespositive regulation of phosphatidylinositol 3-kinase signaling
                                                                        regulatesregulation of phosphatidylinositol 3-kinase signaling +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-ainositol lipid-mediated signaling
                                                        is-aphosphatidylinositol-mediated signaling
                                                                is-aphosphatidylinositol 3-kinase signaling [GO:0014065] (83 genes, 93 annotations)
                                                                        negatively-regulatesnegative regulation of phosphatidylinositol 3-kinase signaling
                                                                        positively-regulatespositive regulation of phosphatidylinositol 3-kinase signaling
                                                                        regulatesregulation of phosphatidylinositol 3-kinase signaling +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-ainositol lipid-mediated signaling
                                                                is-aphosphatidylinositol-mediated signaling
                                                                        is-aphosphatidylinositol 3-kinase signaling [GO:0014065] (83 genes, 93 annotations)
                                                                                negatively-regulatesnegative regulation of phosphatidylinositol 3-kinase signaling
                                                                                positively-regulatespositive regulation of phosphatidylinositol 3-kinase signaling
                                                                                regulatesregulation of phosphatidylinositol 3-kinase signaling +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-ainositol lipid-mediated signaling
                                                        is-aphosphatidylinositol-mediated signaling
                                                                is-aphosphatidylinositol 3-kinase signaling [GO:0014065] (83 genes, 93 annotations)
                                                                        negatively-regulatesnegative regulation of phosphatidylinositol 3-kinase signaling
                                                                        positively-regulatespositive regulation of phosphatidylinositol 3-kinase signaling
                                                                        regulatesregulation of phosphatidylinositol 3-kinase signaling +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-aintracellular signal transduction
                                                is-ainositol lipid-mediated signaling
                                                        is-aphosphatidylinositol-mediated signaling
                                                                is-aphosphatidylinositol 3-kinase signaling [GO:0014065] (83 genes, 93 annotations)
                                                                        negatively-regulatesnegative regulation of phosphatidylinositol 3-kinase signaling
                                                                        positively-regulatespositive regulation of phosphatidylinositol 3-kinase signaling
                                                                        regulatesregulation of phosphatidylinositol 3-kinase signaling +


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-ainositol lipid-mediated signaling
                                                        is-aphosphatidylinositol-mediated signaling
                                                                is-aphosphatidylinositol 3-kinase signaling [GO:0014065] (83 genes, 93 annotations)
                                                                        negatively-regulatesnegative regulation of phosphatidylinositol 3-kinase signaling
                                                                        positively-regulatespositive regulation of phosphatidylinositol 3-kinase signaling
                                                                        regulatesregulation of phosphatidylinositol 3-kinase signaling +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-aintracellular signal transduction
                                                is-ainositol lipid-mediated signaling
                                                        is-aphosphatidylinositol-mediated signaling
                                                                is-aphosphatidylinositol 3-kinase signaling [GO:0014065] (83 genes, 93 annotations)
                                                                        negatively-regulatesnegative regulation of phosphatidylinositol 3-kinase signaling
                                                                        positively-regulatespositive regulation of phosphatidylinositol 3-kinase signaling
                                                                        regulatesregulation of phosphatidylinositol 3-kinase signaling +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-aintracellular signal transduction
                                                        is-ainositol lipid-mediated signaling
                                                                is-aphosphatidylinositol-mediated signaling
                                                                        is-aphosphatidylinositol 3-kinase signaling [GO:0014065] (83 genes, 93 annotations)
                                                                                negatively-regulatesnegative regulation of phosphatidylinositol 3-kinase signaling
                                                                                positively-regulatespositive regulation of phosphatidylinositol 3-kinase signaling
                                                                                regulatesregulation of phosphatidylinositol 3-kinase signaling +


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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory