Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLD2
  • Mouse genes Pld2
  • Rat genes Pld2
  • Zfish genes pld2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pld2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004630	phospholipase D activity	Pld2	IDA		Mouse	PMID:21085684
Molecular Function	GO:0004630	phospholipase D activity	Pld2	IDA		Rat	PMID:9111050|RGD:729617
Molecular Function	GO:0005515	protein binding	PLD2	IPI	UniProtKB:P62993	Human	PMID:16407827
Molecular Function	GO:0005515	protein binding	PLD2	IPI	UniProtKB:P62993	Human	PMID:17276458
Molecular Function	GO:0005515	protein binding	PLD2	IPI	UniProtKB:P23528	Human	PMID:17853892
Molecular Function	GO:0005515	protein binding	PLD2	IPI	UniProtKB:P15153	Human	PMID:22106281
Molecular Function	GO:0005515	protein binding	PLD2	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLD2	IPI	UniProtKB:P13051-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Pld2	IPI	RGD:2091	Rat	PMID:11876650|RGD:2301135
Molecular Function	GO:0005515	protein binding	Pld2	IPI	UniProtKB:P33535	Rat	PMID:12519790|RGD:8553861
Molecular Function	GO:0005080	protein kinase C binding	Pld2	IPI	RGD:3399	Rat	PMID:16113073|RGD:1642674
Cellular Component	GO:0031526	brush border membrane	Pld2	IDA		Mouse	PMID:15598876
Cellular Component	GO:0005901	caveola	Pld2	IDA		Rat	PMID:12429836|RGD:2299914
Cellular Component	GO:0005794	Golgi apparatus	Pld2	IDA		Rat	PMID:12429836|RGD:2299914
Cellular Component	GO:0030027	lamellipodium	Pld2	IDA		Rat	PMID:18344600|RGD:2299899
Cellular Component	GO:0005634	nucleus	Pld2	IDA		Rat	PMID:12429836|RGD:2299914
Cellular Component	GO:0005886	plasma membrane	Pld2	IDA		Mouse	PMID:14718562
Cellular Component	GO:0005886	plasma membrane	Pld2	IDA		Rat	PMID:18344600|RGD:2299899
Cellular Component	GO:0042383	sarcolemma	Pld2	IDA		Rat	PMID:10801846|RGD:2299920
Biological Process	GO:0002031	G protein-coupled receptor internalization	Pld2	IDA		Mouse	PMID:14718562
Biological Process	GO:0031175	neuron projection development	Pld2	IMP		Rat	PMID:18004999|RGD:2299900
Biological Process	GO:0009395	phospholipid catabolic process	Pld2	IMP		Rat	PMID:16459925|RGD:2299904
Biological Process	GO:0045785	positive regulation of cell adhesion	Pld2	IMP		Rat	PMID:15976455|RGD:2299905
Biological Process	GO:0030335	positive regulation of cell migration	Pld2	IMP		Rat	PMID:18344600|RGD:2299899
Biological Process	GO:0043306	positive regulation of mast cell degranulation	Pld2	IMP		Rat	PMID:16861349|RGD:2299903
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Pld2	IMP		Rat	PMID:15705590|RGD:2299907
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	Pld2	IMP		Rat	PMID:15470141|RGD:2299909
Biological Process	GO:0006898	receptor-mediated endocytosis	Pld2	IDA		Mouse	PMID:14718562
Biological Process	GO:0042542	response to hydrogen peroxide	Pld2	IMP		Rat	PMID:15705590|RGD:2299907
Biological Process	GO:0001666	response to hypoxia	Pld2	IDA		Rat	PMID:11095536|RGD:2299918
Biological Process	GO:0014070	response to organic cyclic compound	Pld2	IDA		Rat	PMID:11923096|RGD:2299916
Biological Process	GO:0043434	response to peptide hormone	Pld2	IMP		Rat	PMID:16459925|RGD:2299904

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern