| GO term: | receptor-mediated endocytosis |
| Synonym: | receptor mediated endocytosis |
| GO id: | GO:0006898 |
| Definition: | An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. |
| Number of paths to term: | 2 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processestablishment of localizationtransportvesicle-mediated transportendocytosisnegative regulation of endocytosis +phagocytosis +pinocytosis +positive regulation of endocytosis +receptor-mediated endocytosis [GO:0006898] (114 genes, 146 annotations)caveolin-mediated endocytosis +clathrin-mediated endocytosis +negative regulation of receptor-mediated endocytosis +positive regulation of receptor-mediated endocytosis +receptor internalization +receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transportregulation of receptor-mediated endocytosis +viral entry into host cell via receptor-mediated endocytosis +regulation of endocytosis +sperm entrysynaptic vesicle endocytosis +ubiquitin-dependent endocytosis +biological_processlocalizationestablishment of localizationtransportvesicle-mediated transportendocytosisnegative regulation of endocytosis +phagocytosis +pinocytosis +positive regulation of endocytosis +receptor-mediated endocytosis [GO:0006898] (114 genes, 146 annotations)caveolin-mediated endocytosis +clathrin-mediated endocytosis +negative regulation of receptor-mediated endocytosis +positive regulation of receptor-mediated endocytosis +receptor internalization +receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transportregulation of receptor-mediated endocytosis +viral entry into host cell via receptor-mediated endocytosis +regulation of endocytosis +sperm entrysynaptic vesicle endocytosis +ubiquitin-dependent endocytosis +Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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