Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PKNOX1
  • Mouse genes Pknox1
  • Rat genes Pknox1
  • Zfish genes pknox1.1,pknox1.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pknox1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Pknox1	IDA		Mouse	PMID:22780989
Molecular Function	GO:0003677	DNA binding	Pknox1	IDA		Mouse	PMID:9405651
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Pknox1	IDA		Mouse	PMID:10373562
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:P40424	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:P40424	Human	PMID:25856340
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:A5D8V6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:P26583	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:Q10571	Human	PMID:31839203
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:A5D8V6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:P26583	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:Q13368	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:Q8TC76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:Q8TDH9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:Q96GS4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:Q9BVL2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:Q9BYU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKNOX1	IPI	UniProtKB:Q9BVL2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Pknox1	IPI	PR:Q62432	Mouse	PMID:14764653
Molecular Function	GO:0005515	protein binding	Pknox1	IPI	PR:Q60954	Mouse	PMID:10373562
Molecular Function	GO:0005515	protein binding	Pknox1	IPI	PR:P97471	Mouse	PMID:14764653
Molecular Function	GO:0005515	protein binding	Pknox1	IPI	PR:Q8BUN5	Mouse	PMID:14764653
Molecular Function	GO:0005515	protein binding	Pknox1	IPI	PR:O35317	Mouse	PMID:10381567
Molecular Function	GO:0005515	protein binding	Pknox1	IPI	PR:P41778	Mouse	PMID:9405651
Molecular Function	GO:0005515	protein binding	Pknox1	IPI	PR:P41778	Mouse	PMID:10381567
Molecular Function	GO:0005515	protein binding	Pknox1	IPI	PR:O35984	Mouse	PMID:10381567
Molecular Function	GO:0005515	protein binding	Pknox1	IPI	PR:P41778	Mouse	PMID:14764653
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pknox1	IGI	MGI:MGI:97495	Mouse	PMID:17049510
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pknox1	IDA		Mouse	PMID:10381567
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Pknox1	IDA		Mouse	PMID:14764653
Molecular Function	GO:0043565	sequence-specific DNA binding	Pknox1	IDA		Mouse	MGI:MGI:3777519|PMID:17875925
Molecular Function	GO:0043565	sequence-specific DNA binding	pknox1.1	IDA		Zfish	PMID:24480644
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	PKNOX1	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Pknox1	IDA		Mouse	PMID:15087118
Cellular Component	GO:0005737	cytoplasm	pknox1.1	IDA		Zfish	PMID:14711874
Cellular Component	GO:0005634	nucleus	Pknox1	IDA		Mouse	PMID:16847320
Cellular Component	GO:0005634	nucleus	Pknox1	IDA		Mouse	PMID:17049510
Cellular Component	GO:0005634	nucleus	Pknox1	IDA		Mouse	PMID:15087118
Cellular Component	GO:0005634	nucleus	pknox1.1	IDA		Zfish	PMID:14711874
Cellular Component	GO:0005667	transcription regulator complex	Pknox1	IDA		Mouse	PMID:9405651
Cellular Component	GO:0005667	transcription regulator complex	Pknox1	IDA		Mouse	PMID:10373562
Cellular Component	GO:0005667	transcription regulator complex	Pknox1	IDA		Mouse	PMID:17049510
Cellular Component	GO:0005667	transcription regulator complex	Pknox1	IDA		Mouse	PMID:10381567
Cellular Component	GO:0005667	transcription regulator complex	Pknox1	IDA		Mouse	PMID:14764653
Biological Process	GO:0001525	angiogenesis	Pknox1	IMP	MGI:MGI:3530910	Mouse	PMID:16847320
Biological Process	GO:0043010	camera-type eye development	Pknox1	IMP	MGI:MGI:3530910	Mouse	PMID:16847320
Biological Process	GO:0030218	erythrocyte differentiation	Pknox1	IMP	MGI:MGI:3530910	Mouse	PMID:16847320
Biological Process	GO:0030097	hemopoiesis	Pknox1	IMP	MGI:MGI:3530910	Mouse	PMID:17904118
Biological Process	GO:0030902	hindbrain development	pknox1.1	IMP	ZFIN:ZDB-MRPHLNO-060930-14	Zfish	PMID:14711874
Biological Process	GO:0031061	negative regulation of histone methylation	pknox1.1	IGI	ZFIN:ZDB-GENE-000201-18	Zfish	PMID:24480644
Biological Process	GO:0014033	neural crest cell differentiation	pknox1.1	IMP	ZFIN:ZDB-MRPHLNO-060930-14	Zfish	PMID:14711874
Biological Process	GO:0060037	pharyngeal system development	pknox1.2	IMP	ZFIN:ZDB-MRPHLNO-100701-1	Zfish	PMID:20423710
Biological Process	GO:0035066	positive regulation of histone acetylation	pknox1.1	IGI	ZFIN:ZDB-GENE-000201-18,ZFIN:ZDB-GENE-980526-290	Zfish	PMID:24480644
Biological Process	GO:0035066	positive regulation of histone acetylation	pknox1.1	IGI	ZFIN:ZDB-GENE-000201-18	Zfish	PMID:24480644
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pknox1	IDA		Mouse	PMID:10381567
Biological Process	GO:0031060	regulation of histone methylation	pknox1.1	IGI	ZFIN:ZDB-GENE-000201-18,ZFIN:ZDB-GENE-980526-290	Zfish	PMID:24480644
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Pknox1	IDA		Mouse	PMID:10373562
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	pknox1.2	IMP	ZFIN:ZDB-MRPHLNO-100701-1	Zfish	PMID:20423710
Biological Process	GO:0030217	T cell differentiation	Pknox1	IMP	MGI:MGI:3530910	Mouse	PMID:16314502

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern