Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PGF
  • Mouse genes Pgf
  • Rat genes Pgf
  • Zfish genes pgfa,pgfb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pgf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008083	growth factor activity	PGF	IMP		Human	PMID:21215706
Molecular Function	GO:0042802	identical protein binding	Pgf	IPI	RGD:619850	Rat	PMID:7706320|RGD:633657
Molecular Function	GO:0005515	protein binding	PGF	IPI	UniProtKB:P17948	Human	PMID:14684734
Molecular Function	GO:0005515	protein binding	PGF	IPI	UniProtKB:P17948	Human	PMID:20660291
Molecular Function	GO:0044877	protein-containing complex binding	Pgf	IDA		Rat	PMID:7706320|RGD:633657
Cellular Component	GO:0005615	extracellular space	Pgf	IDA		Mouse	PMID:25184477
Cellular Component	GO:0005615	extracellular space	Pgf	IDA		Rat	PMID:17240241|RGD:1642388
Biological Process	GO:0031100	animal organ regeneration	Pgf	IEP		Rat	PMID:21088600|RGD:6483778
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	Pgf	IDA		Mouse	PMID:13678594
Biological Process	GO:0032870	cellular response to hormone stimulus	Pgf	IEP		Rat	PMID:9400995|RGD:1642393
Biological Process	GO:0007565	female pregnancy	Pgf	IEP		Rat	PMID:16131818|RGD:1642392
Biological Process	GO:0045766	positive regulation of angiogenesis	Pgf	IDA		Rat	PMID:21329947|RGD:6483777
Biological Process	GO:0008284	positive regulation of cell population proliferation	PGF	IMP		Human	PMID:21215706
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	Pgf	IMP		Rat	PMID:9400995|RGD:1642393
Biological Process	GO:0060688	regulation of morphogenesis of a branching structure	Pgf	IDA		Mouse	PMID:13678594
Biological Process	GO:0001666	response to hypoxia	Pgf	IEP		Rat	PMID:17240241|RGD:1642388
Biological Process	GO:0009410	response to xenobiotic stimulus	Pgf	IEP		Rat	PMID:9400995|RGD:1642393
Biological Process	GO:0002040	sprouting angiogenesis	Pgf	IDA		Rat	PMID:21408222|RGD:6483775

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern