Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OSR2
  • Mouse genes Osr2
  • Rat genes Osr2
  • Zfish genes osr2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Osr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Osr2	IDA		Mouse	MGI:MGI:3818159|PMID:17547533
Molecular Function	GO:0005515	protein binding	OSR2	IPI	UniProtKB:P25788	Human	PMID:25416956
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Osr2	IDA		Mouse	MGI:MGI:3818159|PMID:17547533
Molecular Function	GO:0043565	sequence-specific DNA binding	Osr2	IDA		Mouse	MGI:MGI:3818159|PMID:17547533
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	OSR2	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Osr2	IDA		Mouse	MGI:MGI:3818159|PMID:17547533
Biological Process	GO:0060349	bone morphogenesis	Osr2	IMP		Mouse	MGI:MGI:3818159|PMID:17547533
Biological Process	GO:0030154	cell differentiation	Osr2	IGI	UniProtKB:Q9WVG7	Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0008283	cell population proliferation	Osr2	IMP	MGI:MGI:3033240	Mouse	PMID:15175245
Biological Process	GO:0002062	chondrocyte differentiation	Osr2	IGI	UniProtKB:Q9WVG7	Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	Osr2	IEP		Mouse	MGI:MGI:2149941|PMID:11520675
Biological Process	GO:0042733	embryonic digit morphogenesis	Osr2	IGI	UniProtKB:Q9WVG7	Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Osr2	IEP		Mouse	MGI:MGI:2149941|PMID:11520675
Biological Process	GO:0035115	embryonic forelimb morphogenesis	Osr2	IGI	UniProtKB:Q9WVG7	Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	Osr2	IEP		Mouse	MGI:MGI:2149941|PMID:11520675
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	Osr2	IGI	UniProtKB:Q9WVG7	Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0072498	embryonic skeletal joint development	Osr2	IGI	UniProtKB:Q9WVG7	Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0060272	embryonic skeletal joint morphogenesis	Osr2	IMP		Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0036023	embryonic skeletal limb joint morphogenesis	Osr2	IGI	UniProtKB:Q9WVG7	Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Osr2	IMP	MGI:MGI:3033240	Mouse	PMID:15175245
Biological Process	GO:0061029	eyelid development in camera-type eye	Osr2	IMP		Mouse	MGI:MGI:3848564|PMID:19389375
Biological Process	GO:0060322	head development	Osr2	IMP		Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0001822	kidney development	osr2	IMP	ZFIN:ZDB-MRPHLNO-070321-4	Zfish	PMID:17011543
Biological Process	GO:0001822	kidney development	osr2	IDA		Zfish	PMID:17011543
Biological Process	GO:0001823	mesonephros development	Osr2	IEP		Mouse	MGI:MGI:2149941|PMID:11520675
Biological Process	GO:0001656	metanephros development	Osr2	IEP		Mouse	MGI:MGI:2149941|PMID:11520675
Biological Process	GO:0042474	middle ear morphogenesis	Osr2	IMP		Mouse	MGI:MGI:3848564|PMID:19389375
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	osr2	IMP		Zfish	PMID:17011543|ZFIN:ZDB-PUB-061020-6
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Osr2	IGI	UniProtKB:Q9WVG7	Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	osr2	IMP		Zfish	PMID:17011543|ZFIN:ZDB-PUB-061020-6
Biological Process	GO:0042476	odontogenesis	Osr2	IMP		Mouse	MGI:MGI:3848564|PMID:19389375
Biological Process	GO:0033687	osteoblast proliferation	Osr2	IMP		Mouse	MGI:MGI:3818159|PMID:17547533
Biological Process	GO:0033339	pectoral fin development	osr2	IGI	ZFIN:ZDB-MRPHLNO-070321-3,ZFIN:ZDB-MRPHLNO-070321-4	Zfish	PMID:22129829
Biological Process	GO:0033339	pectoral fin development	osr2	IGI	ZFIN:ZDB-MRPHLNO-090121-1,ZFIN:ZDB-MRPHLNO-120127-7	Zfish	PMID:22129829
Biological Process	GO:0033339	pectoral fin development	osr2	IMP	ZFIN:ZDB-MRPHLNO-131217-3,ZFIN:ZDB-MRPHLNO-131217-4	Zfish	PMID:23913342
Biological Process	GO:0033339	pectoral fin development	osr2	IMP	ZFIN:ZDB-MRPHLNO-070321-4	Zfish	PMID:22129829
Biological Process	GO:0033339	pectoral fin development	osr2	IMP	ZFIN:ZDB-MRPHLNO-120127-7	Zfish	PMID:22129829
Biological Process	GO:0030501	positive regulation of bone mineralization	Osr2	IGI	UniProtKB:Q9WVG7	Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Osr2	IMP		Mouse	MGI:MGI:3818159|PMID:17547533
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Osr2	IMP		Mouse	MGI:MGI:3848564|PMID:19389375
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Osr2	IMP		Mouse	MGI:MGI:3848564|PMID:19389375
Biological Process	GO:2000543	positive regulation of gastrulation	Osr2	IMP		Mouse	MGI:MGI:5009762|PMID:21281489
Biological Process	GO:0010628	positive regulation of gene expression	Osr2	IMP		Mouse	MGI:MGI:3848564|PMID:19389375
Biological Process	GO:0010628	positive regulation of gene expression	Osr2	IMP		Mouse	MGI:MGI:3818159|PMID:17547533
Biological Process	GO:2000648	positive regulation of stem cell proliferation	Osr2	IMP	MGI:MGI:3033240	Mouse	PMID:15175245
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Osr2	IDA		Mouse	MGI:MGI:3818159|PMID:17547533
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Osr2	IGI	UniProtKB:Q9WVG7	Mouse	MGI:MGI:4950000|PMID:21262216
Biological Process	GO:0048793	pronephros development	Osr2	IMP		Mouse	MGI:MGI:5009762|PMID:21281489
Biological Process	GO:0048793	pronephros development	osr2	IDA		Zfish	PMID:17011543
Biological Process	GO:0060021	roof of mouth development	Osr2	IMP		Mouse	MGI:MGI:3848564|PMID:19389375
Biological Process	GO:0072089	stem cell proliferation	Osr2	IMP	MGI:MGI:3033240	Mouse	PMID:15175245

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern