Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ORM1,ORM2
  • Mouse genes Orm2
  • Rat genes Orm1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Orm2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ORM1	IPI	UniProtKB:P05121	Human	PMID:16272158
Molecular Function	GO:0036094	small molecule binding	Orm1	IDA		Rat	PMID:3252025|RGD:2316648
Cellular Component	GO:0072562	blood microparticle	ORM1	HDA		Human	PMID:22516433
Cellular Component	GO:0072562	blood microparticle	ORM2	HDA		Human	PMID:22516433
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ORM1	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ORM2	HDA		Human	PMID:27559042
Cellular Component	GO:0070062	extracellular exosome	ORM1	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	ORM2	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	ORM1	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	ORM1	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	ORM1	IDA		Human	PMID:8774350
Cellular Component	GO:0005615	extracellular space	ORM2	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	ORM2	IDA		Human	PMID:8774350
Cellular Component	GO:0005615	extracellular space	Orm1	IDA		Rat	PMID:11408029|RGD:2316643
Biological Process	GO:0002438	acute inflammatory response to antigenic stimulus	Orm1	IEP		Rat	PMID:15771231|RGD:1625398
Biological Process	GO:0031100	animal organ regeneration	Orm1	IEP		Rat	PMID:11350548|RGD:2316644
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Orm1	IEP		Rat	PMID:10453035|RGD:2316645
Biological Process	GO:0071378	cellular response to growth hormone stimulus	Orm1	IEP		Rat	PMID:9862866|RGD:2316647
Biological Process	GO:0071300	cellular response to retinoic acid	Orm1	IEP		Rat	PMID:15157739|RGD:2316642
Biological Process	GO:0002439	chronic inflammatory response to antigenic stimulus	Orm1	IEP		Rat	PMID:16166348|RGD:2316639
Biological Process	GO:0032715	negative regulation of interleukin-6 production	ORM1	IDA		Human	PMID:23973664
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ORM1	IDA		Human	PMID:23973664
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	ORM1	IDA		Human	PMID:8774350
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	ORM2	IDA		Human	PMID:8774350
Biological Process	GO:0032732	positive regulation of interleukin-1 production	ORM1	IDA		Human	PMID:8774350
Biological Process	GO:0032732	positive regulation of interleukin-1 production	ORM2	IDA		Human	PMID:8774350
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ORM1	IDA		Human	PMID:8774350
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ORM2	IDA		Human	PMID:8774350
Biological Process	GO:0032496	response to lipopolysaccharide	Orm1	IEP		Rat	PMID:11350548|RGD:2316644
Biological Process	GO:0014070	response to organic cyclic compound	Orm1	IEP		Rat	PMID:16300371|RGD:2316638
Biological Process	GO:0033197	response to vitamin E	Orm1	IEP		Rat	PMID:11444866|RGD:1601045
Biological Process	GO:0009410	response to xenobiotic stimulus	Orm1	IEP		Rat	PMID:11408029|RGD:2316643
Biological Process	GO:0009410	response to xenobiotic stimulus	Orm1	IEP		Rat	PMID:9920738|RGD:2316646

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern