Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Olig2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes OLIG2
- Mouse genes Olig2
- Rat genes Olig2
- Zfish genes olig2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Olig2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Olig2	IDA		Mouse	PMID:14573534
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Olig2	IDA		Mouse	PMID:15655114
Molecular Function	GO:0071837	HMG box domain binding	Olig2	IPI	UniProtKB:O55170\|UniProtKB:Q04886\|UniProtKB:Q05066	Mouse	MGI:MGI:5284787\|PMID:16582099
Molecular Function	GO:0042802	identical protein binding	Olig2	IPI	PR:Q9EQW6	Mouse	PMID:15655114
Molecular Function	GO:0005515	protein binding	OLIG2	IPI	UniProtKB:P40222	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OLIG2	IPI	UniProtKB:P60329	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Olig2	IPI	UniProtKB:P41136\|UniProtKB:P41139	Mouse	MGI:MGI:3706482\|PMID:15280210
Molecular Function	GO:0005515	protein binding	Olig2	IPI	PR:Q5HZG9	Mouse	PMID:16908628
Molecular Function	GO:0005515	protein binding	Olig2	IPI	PR:P42586	Mouse	PMID:14573534
Molecular Function	GO:0005515	protein binding	Olig2	IPI	PR:P70447	Mouse	PMID:15655114
Molecular Function	GO:0005515	protein binding	Olig2	IPI	UniProtKB:Q8K1P7	Rat	PMID:23332759\|RGD:8554496
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	OLIG2	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Olig2	IDA		Mouse	PMID:14573534
Cellular Component	GO:0005634	nucleus	Olig2	IDA		Mouse	PMID:14573534
Cellular Component	GO:0005634	nucleus	Olig2	IDA		Mouse	PMID:20181579
Biological Process	GO:0021742	abducens nucleus development	olig2	IMP	ZFIN:ZDB-MRPHLNO-090821-5	Zfish	PMID:19244509
Biological Process	GO:0071542	dopaminergic neuron differentiation	olig2	IMP	ZFIN:ZDB-MRPHLNO-050204-2	Zfish	PMID:19253397
Biological Process	GO:0071542	dopaminergic neuron differentiation	olig2	IGI	ZFIN:ZDB-GENE-020829-1,ZFIN:ZDB-MRPHLNO-050204-2	Zfish	PMID:19253397
Biological Process	GO:0021754	facial nucleus development	olig2	IMP	ZFIN:ZDB-MRPHLNO-090821-5	Zfish	PMID:22275004
Biological Process	GO:0007403	glial cell fate determination	olig2	IMP		Zfish	PMID:12167410
Biological Process	GO:0042552	myelination	Olig2	IMP	MGI:MGI:2179048,MGI:MGI:3614399	Mouse	PMID:16436615
Biological Process	GO:0045665	negative regulation of neuron differentiation	Olig2	IDA		Mouse	PMID:11566099
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Olig2	IDA		Mouse	PMID:15655114
Biological Process	GO:0007399	nervous system development	Olig2	IDA		Mouse	PMID:14573534
Biological Process	GO:0007400	neuroblast fate determination	olig2	IMP		Zfish	PMID:12167410
Biological Process	GO:0048666	neuron development	olig2	IMP	ZFIN:ZDB-MRPHLNO-050204-2	Zfish	PMID:21828101
Biological Process	GO:0030182	neuron differentiation	Olig2	IDA		Mouse	PMID:11566099
Biological Process	GO:0048663	neuron fate commitment	Olig2	IMP	MGI:MGI:2179312	Mouse	PMID:11955448
Biological Process	GO:0001764	neuron migration	olig2	IMP	ZFIN:ZDB-MRPHLNO-090821-5	Zfish	PMID:22275004
Biological Process	GO:0014003	oligodendrocyte development	olig2	IMP	ZFIN:ZDB-MRPHLNO-050204-2	Zfish	PMID:19253391
Biological Process	GO:0014003	oligodendrocyte development	olig2	IMP		Zfish	PMID:12167410
Biological Process	GO:0048709	oligodendrocyte differentiation	Olig2	IMP	MGI:MGI:2179048,MGI:MGI:3614399	Mouse	PMID:16436615
Biological Process	GO:0048709	oligodendrocyte differentiation	Olig2	IGI	MGI:MGI:97347	Mouse	PMID:11566099
Biological Process	GO:0048709	oligodendrocyte differentiation	Olig2	IMP		Rat	PMID:22173726\|RGD:40902844
Biological Process	GO:0048709	oligodendrocyte differentiation	olig2	IMP	ZFIN:ZDB-MRPHLNO-090821-5	Zfish	PMID:19244509
Biological Process	GO:0050769	positive regulation of neurogenesis	olig2	IMP		Zfish	PMID:12167410
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	Olig2	IGI	MGI:MGI:97347	Mouse	PMID:11566099
Biological Process	GO:0006355	regulation of DNA-templated transcription	Olig2	IDA		Mouse	PMID:14573534
Biological Process	GO:0021520	spinal cord motor neuron cell fate specification	olig2	IMP	ZFIN:ZDB-MRPHLNO-050204-2	Zfish	PMID:12167410
Biological Process	GO:0021522	spinal cord motor neuron differentiation	Olig2	IMP	MGI:MGI:3774124	Mouse	PMID:21338882
Biological Process	GO:0021522	spinal cord motor neuron differentiation	olig2	IMP	ZFIN:ZDB-MRPHLNO-070615-3	Zfish	PMID:17389390
Biological Process	GO:0021529	spinal cord oligodendrocyte cell differentiation	Olig2	IGI	MGI:MGI:96919	Mouse	PMID:18287202
Biological Process	GO:0021530	spinal cord oligodendrocyte cell fate specification	Olig2	IDA		Mouse	PMID:18287202
Biological Process	GO:0021794	thalamus development	Olig2	IMP		Mouse	PMID:19357274
Biological Process	GO:0021514	ventral spinal cord interneuron differentiation	olig2	IMP	ZFIN:ZDB-MRPHLNO-100901-2	Zfish	PMID:20610488

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.