Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NUCB1
  • Mouse genes Nucb1
  • Rat genes Nucb1
  • Zfish genes nucb1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nucb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Nucb1	IDA		Rat	PMID:9647645|RGD:9831131
Molecular Function	GO:0001965	G-protein alpha-subunit binding	Nucb1	IDA		Rat	PMID:21653697|RGD:14929204
Molecular Function	GO:0001965	G-protein alpha-subunit binding	Nucb1	IDA		Rat	PMID:9647645|RGD:9831131
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Nucb1	IDA		Rat	PMID:21653697|RGD:14929204
Molecular Function	GO:0005515	protein binding	NUCB1	IPI	UniProtKB:Q99IB8:PRO_0000045603	Human	PMID:24136289
Molecular Function	GO:0005515	protein binding	NUCB1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nucb1	IPI	RGD:1321391	Rat	PMID:19497050|RGD:9831132
Cellular Component	GO:0005801	cis-Golgi network	Nucb1	IDA		Rat	PMID:9647645|RGD:9831131
Cellular Component	GO:0005737	cytoplasm	Nucb1	IDA		Rat	PMID:15193541|RGD:9831129
Cellular Component	GO:0005769	early endosome	Nucb1	IDA		Rat	PMID:19497050|RGD:9831132
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	NUCB1	IDA		Human	PMID:15308636
Cellular Component	GO:0070062	extracellular exosome	NUCB1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	NUCB1	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	Nucb1	IDA		Rat	PMID:15193541|RGD:9831129
Cellular Component	GO:0005615	extracellular space	NUCB1	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	Nucb1	IDA		Rat	PMID:12403836|RGD:9831143
Cellular Component	GO:0090498	extrinsic component of Golgi membrane	Nucb1	IDA		Rat	PMID:9647645|RGD:9831131
Cellular Component	GO:0005794	Golgi apparatus	Nucb1	IDA		Rat	PMID:10209024|RGD:9831124
Cellular Component	GO:0032580	Golgi cisterna membrane	Nucb1	IDA		Rat	PMID:9647645|RGD:9831131
Cellular Component	GO:0005798	Golgi-associated vesicle	Nucb1	IDA		Rat	PMID:9647645|RGD:9831131
Cellular Component	GO:0098547	lumenal side of Golgi membrane	Nucb1	IDA		Rat	PMID:9647645|RGD:9831131
Cellular Component	GO:0016020	membrane	NUCB1	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	Nucb1	IDA		Rat	PMID:15193541|RGD:9831129
Cellular Component	GO:0005791	rough endoplasmic reticulum	Nucb1	IDA		Rat	PMID:15193541|RGD:9831129
Cellular Component	GO:0005802	trans-Golgi network	Nucb1	IDA		Rat	PMID:19497050|RGD:9831132
Biological Process	GO:1903533	regulation of protein targeting	Nucb1	IDA		Rat	PMID:19497050|RGD:9831132
Biological Process	GO:0072718	response to cisplatin	Nucb1	IEP		Rat	PMID:17321087|RGD:9831176
Biological Process	GO:0007264	small GTPase mediated signal transduction	Nucb1	IDA		Rat	PMID:21653697|RGD:14929204

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern