Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NRN1
  • Mouse genes Nrn1
  • Rat genes Nrn1
  • Zfish genes nrn1a,nrn1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nrn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Nrn1	IPI	PR:Q8CFV4	Mouse	PMID:18265009
Molecular Function	GO:0005515	protein binding	Nrn1	IPI	PR:Q8C4W3	Mouse	PMID:18265009
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Nrn1	IDA		Mouse	PMID:22632720
Cellular Component	GO:0005615	extracellular space	Nrn1	IDA		Mouse	PMID:18265009
Cellular Component	GO:0098978	glutamatergic synapse	Nrn1	IDA		Mouse	PMID:28475719
Cellular Component	GO:0098978	glutamatergic synapse	Nrn1	IEP		Mouse	PMID:28475719
Cellular Component	GO:0098978	glutamatergic synapse	Nrn1	EXP		Mouse	PMID:28475719
Cellular Component	GO:0098978	glutamatergic synapse	Nrn1	IMP		Mouse	PMID:28475719
Cellular Component	GO:0005886	plasma membrane	Nrn1	IDA		Mouse	PMID:18265009
Cellular Component	GO:0098793	presynapse	Nrn1	IDA		Mouse	MGI:MGI:5908484|PMID:28475719
Biological Process	GO:0007399	nervous system development	Nrn1	IDA		Rat	PMID:9122250|RGD:633434
Biological Process	GO:1990138	neuron projection extension	Nrn1	IDA		Mouse	PMID:18265009
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Nrn1	EXP		Mouse	PMID:28475719
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Nrn1	IDA		Mouse	PMID:28475719
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Nrn1	IEP		Mouse	PMID:28475719
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Nrn1	IMP		Mouse	PMID:28475719

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern