Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NRCAM
  • Mouse genes Nrcam
  • Rat genes Nrcam
  • Zfish genes nrcama,nrcamb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nrcam

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030506	ankyrin binding	NRCAM	IDA		Human	PMID:14602817
Molecular Function	GO:0005515	protein binding	NRCAM	IPI	UniProtKB:Q99972	Human	PMID:23897819
Molecular Function	GO:0005515	protein binding	Nrcam	IPI	UniProtKB:O70624	Mouse	MGI:MGI:5527213|PMID:23897819
Molecular Function	GO:0005515	protein binding	Nrcam	IPI	PR:Q811D0	Mouse	PMID:16882004
Molecular Function	GO:0005515	protein binding	Nrcam	IPI	PR:Q62108	Mouse	PMID:16882004
Molecular Function	GO:0086080	protein binding involved in heterotypic cell-cell adhesion	Nrcam	IGI	MGI:MGI:2388361	Mouse	PMID:20188654
Cellular Component	GO:0030424	axon	Nrcam	IDA		Mouse	PMID:14602817
Cellular Component	GO:0030424	axon	Nrcam	IDA		Rat	PMID:17709431|RGD:14392774
Cellular Component	GO:0043194	axon initial segment	Nrcam	IDA		Rat	PMID:11724816|RGD:8553674
Cellular Component	GO:0043194	axon initial segment	Nrcam	IDA		Rat	PMID:17709431|RGD:14392774
Cellular Component	GO:0098978	glutamatergic synapse	Nrcam	IDA		Mouse	PMID:25143608
Cellular Component	GO:0098978	glutamatergic synapse	Nrcam	IEP		Mouse	PMID:25143608
Cellular Component	GO:0098978	glutamatergic synapse	Nrcam	IMP		Mouse	PMID:25143608
Cellular Component	GO:0033268	node of Ranvier	Nrcam	IDA		Rat	PMID:17709431|RGD:14392774
Cellular Component	GO:0005886	plasma membrane	Nrcam	IDA		Mouse	PMID:16882004
Cellular Component	GO:0098839	postsynaptic density membrane	Nrcam	IDA		Mouse	PMID:25143608
Cellular Component	GO:0098839	postsynaptic density membrane	Nrcam	IEP		Mouse	PMID:25143608
Cellular Component	GO:0045211	postsynaptic membrane	Nrcam	IDA		Mouse	PMID:25143608
Cellular Component	GO:0045202	synapse	Nrcam	IDA		Mouse	PMID:16882004
Biological Process	GO:0001525	angiogenesis	NRCAM	IEP		Human	PMID:11866539
Biological Process	GO:0007411	axon guidance	Nrcam	IDA		Mouse	MGI:MGI:2447374|PMID:12182881
Biological Process	GO:0098609	cell-cell adhesion	Nrcam	IDA		Mouse	MGI:MGI:2447374|PMID:12182881
Biological Process	GO:0007417	central nervous system development	NRCAM	IMP		Human	PMID:35108495
Biological Process	GO:0007417	central nervous system development	Nrcam	IDA		Mouse	MGI:MGI:2447374|PMID:12182881
Biological Process	GO:0045162	clustering of voltage-gated sodium channels	NRCAM	IDA		Human	PMID:14602817
Biological Process	GO:0045162	clustering of voltage-gated sodium channels	Nrcam	IMP	MGI:MGI:2387976	Mouse	PMID:20188654
Biological Process	GO:0019227	neuronal action potential propagation	Nrcam	IMP	MGI:MGI:2387976	Mouse	PMID:14602817
Biological Process	GO:0008104	protein localization	Nrcam	IDA		Mouse	PMID:16882004
Biological Process	GO:0010975	regulation of neuron projection development	Nrcam	IMP	MGI:MGI:2387976	Mouse	PMID:16701205
Biological Process	GO:0099175	regulation of postsynapse organization	Nrcam	IDA		Mouse	PMID:25143608
Biological Process	GO:0099175	regulation of postsynapse organization	Nrcam	IMP		Mouse	PMID:25143608
Biological Process	GO:0031290	retinal ganglion cell axon guidance	Nrcam	IMP	MGI:MGI:2387976	Mouse	PMID:16701205

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern