Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NR2E3
  • Mouse genes Nr2e3
  • Rat genes Nr2e3
  • Zfish genes nr2e3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr2e3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	NR2E3	IMP		Human	PMID:22174013
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Nr2e3	IDA		Mouse	PMID:15689355
Molecular Function	GO:0005515	protein binding	NR2E3	IPI	UniProtKB:P61964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Nr2e3	IPI	PR:O54751	Mouse	PMID:15689355
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NR2E3	IDA		Human	PMID:10220376
Molecular Function	GO:0043565	sequence-specific DNA binding	NR2E3	IDA		Human	PMID:10220376
Cellular Component	GO:0005634	nucleus	Nr2e3	IDA		Mouse	PMID:15689355
Cellular Component	GO:0005634	nucleus	nr2e3	IDA		Zfish	PMID:15634773
Cellular Component	GO:0005667	transcription regulator complex	Nr2e3	IDA		Mouse	PMID:15689355
Biological Process	GO:0008283	cell population proliferation	Nr2e3	IMP	MGI:MGI:1346317	Mouse	PMID:12407160
Biological Process	GO:0042462	eye photoreceptor cell development	Nr2e3	IMP		Mouse	PMID:21052544
Biological Process	GO:0008285	negative regulation of cell population proliferation	Nr2e3	IMP	MGI:MGI:1346317	Mouse	PMID:12407160
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr2e3	IGI	MGI:MGI:1194883	Mouse	PMID:15689355
Biological Process	GO:0045494	photoreceptor cell maintenance	nr2e3	IMP	ZFIN:ZDB-GENO-201130-1	Zfish	PMID:30684641
Biological Process	GO:0021982	pineal gland development	nr2e3	IMP	ZFIN:ZDB-MRPHLNO-161003-2	Zfish	PMID:27317804
Biological Process	GO:0010628	positive regulation of gene expression	Nr2e3	IGI	MGI:MGI:102567	Mouse	PMID:15689355
Biological Process	GO:0010628	positive regulation of gene expression	Nr2e3	IGI	MGI:MGI:1194883	Mouse	PMID:15689355
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NR2E3	IDA		Human	PMID:22174013
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NR2E3	IMP		Human	PMID:22174013
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nr2e3	IGI	MGI:MGI:1194883	Mouse	PMID:15689355
Biological Process	GO:0060041	retina development in camera-type eye	Nr2e3	IMP	MGI:MGI:1346317	Mouse	PMID:12407160
Biological Process	GO:0060041	retina development in camera-type eye	Nr2e3	IMP		Mouse	PMID:21052544
Biological Process	GO:0060221	retinal rod cell differentiation	nr2e3	IMP	ZFIN:ZDB-GENO-201130-1	Zfish	PMID:30684641

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern