Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NELL2
  • Mouse genes Nell2
  • Rat genes Nell2
  • Zfish genes nell2a,nell2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nell2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008201	heparin binding	Nell2	IDA		Rat	PMID:10548494|RGD:633407
Molecular Function	GO:0042802	identical protein binding	Nell2	IPI	RGD:620999	Rat	PMID:10548494|RGD:633407
Molecular Function	GO:0005515	protein binding	NELL2	IPI	UniProtKB:Q5VTD9	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	NELL2	IPI	UniProtKB:P49639	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	NELL2	IPI	UniProtKB:Q7Z417	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	NELL2	IPI	UniProtKB:Q9BYB0	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	NELL2	IPI	UniProtKB:Q9UIS9	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	NELL2	IPI	UniProtKB:P08922	Human	PMID:32499443
Molecular Function	GO:0005080	protein kinase C binding	Nell2	IDA		Rat	PMID:10600492|RGD:633406
Cellular Component	GO:0005737	cytoplasm	Nell2	IDA		Rat	PMID:10548494|RGD:633407
Cellular Component	GO:0030425	dendrite	Nell2	IDA		Rat	PMID:10548494|RGD:633407
Cellular Component	GO:0005576	extracellular region	Nell2	IDA		Mouse	MGI:MGI:6436781|PMID:32499443
Cellular Component	GO:0005615	extracellular space	Nell2	IDA		Rat	PMID:10548494|RGD:633407
Cellular Component	GO:0016020	membrane	Nell2	IDA		Rat	PMID:10548494|RGD:633407
Cellular Component	GO:0043204	perikaryon	Nell2	IDA		Rat	PMID:10548494|RGD:633407
Biological Process	GO:0046543	development of secondary female sexual characteristics	Nell2	IMP		Rat	PMID:18547942|RGD:10047268
Biological Process	GO:0009566	fertilization	Nell2	IMP		Mouse	MGI:MGI:6436781|PMID:32499443
Biological Process	GO:0070050	neuron cellular homeostasis	Nell2	IDA		Rat	PMID:12941464|RGD:10047222
Biological Process	GO:0046887	positive regulation of hormone secretion	Nell2	IMP		Rat	PMID:18547942|RGD:10047268
Biological Process	GO:0040008	regulation of growth	Nell2	IDA		Rat	PMID:10548494|RGD:633407

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern