Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NAPSA
  • Mouse genes Napsa
  • Rat genes Napsa
  • Zfish genes napsa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Napsa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004175	endopeptidase activity	NAPSA	IDA		Human	PMID:14766755
Molecular Function	GO:0004175	endopeptidase activity	Napsa	IMP		Mouse	MGI:MGI:5306315|PMID:14766755
Molecular Function	GO:0008233	peptidase activity	NAPSA	IDA		Human	PMID:18216060
Molecular Function	GO:0005515	protein binding	NAPSA	IPI	UniProtKB:Q5T7P3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NAPSA	IPI	UniProtKB:Q5TA76	Human	PMID:32296183
Cellular Component	GO:0097208	alveolar lamellar body	NAPSA	IDA		Human	PMID:18216060
Cellular Component	GO:0097208	alveolar lamellar body	Napsa	IDA		Mouse	MGI:MGI:5306315|PMID:14766755
Cellular Component	GO:0070062	extracellular exosome	NAPSA	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	NAPSA	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	NAPSA	IDA		Human	PMID:18216060
Cellular Component	GO:0005764	lysosome	NAPSA	IDA		Human	PMID:14766755
Cellular Component	GO:0005764	lysosome	Napsa	IDA		Mouse	MGI:MGI:5306315|PMID:14766755
Biological Process	GO:0033619	membrane protein proteolysis	NAPSA	IDA		Human	PMID:14766755
Biological Process	GO:0033619	membrane protein proteolysis	Napsa	IMP		Mouse	MGI:MGI:5306315|PMID:14766755
Biological Process	GO:0043129	surfactant homeostasis	NAPSA	IDA		Human	PMID:18216060

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern