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Napsa Gene Detail
Summary
  • Symbol
    Napsa
  • Name
    napsin A aspartic peptidase
  • Synonyms
    Kdap, NAP1, napsin, pronapsin
  • Feature Type
    protein coding gene
  • IDs
    MGI:109365
    NCBI Gene: 16541
  • Gene Overview
    MyGene.info: NAPSA
Location & Maps
more
  • Sequence Map
    Chr7:44572380-44586862 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14483 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    NAPSA, napsin A aspartic peptidase
  • Vertebrate Orthologs
    7
  • Human Ortholog
    NAPSA, napsin A aspartic peptidase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    KAP, Kdap, NAP1, NAPA, SNAPA
  • Links
    NCBI Gene ID: 9476
    neXtProt AC: NX_O96009

  • Chr Location
    19q13.33; chr19:50358472-50369331 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021117 VEGA Gene Model | MGI Sequence Detail 14483 C57BL/6J ±  kb
transcript OTTMUST00000049974 VEGA | MGI Sequence Detail 1560 Not Applicable  
polypeptide OTTMUSP00000023258 VEGA | MGI Sequence Detail 419 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    169 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 10
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-38410
References
more
  • Summaries
    All 45
    Developmental Gene Expression 15
    Gene Ontology 7
    Phenotypes 2
  • Earliest
    J:38131 Mori K, et al., Molecular cloning of a novel mouse aspartic protease-like protein that is expressed abundantly in the kidney. FEBS Lett. 1997 Jan 20;401(2-3):218-22
  • Latest
    J:213127 Jakus Z, et al., Lymphatic function is required prenatally for lung inflation at birth. J Exp Med. 2014 May 5;211(5):815-26

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory