About   Help   FAQ
Napsa Gene Detail
Summary
  • Symbol
    Napsa
  • Name
    napsin A aspartic peptidase
  • Synonyms
    Kdap, NAP1, napsin, pronapsin
  • Feature Type
    protein coding gene
  • IDs
    MGI:109365
    NCBI Gene: 16541
  • Gene Overview
    MyGene.info: NAPSA
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:44572445-44586846 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 28.84 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    168 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109365
protein coding gene Chr7:44572380-44586862 (.)
129S1/SvImJ MGP_129S1SvImJ_G0032170
protein coding gene Chr7:44751378-44765364 (+)
A/J MGP_AJ_G0032149
protein coding gene Chr7:43930194-43946725 (+)
AKR/J MGP_AKRJ_G0032085
protein coding gene Chr7:45134716-45153483 (+)
BALB/cJ MGP_BALBcJ_G0032161
protein coding gene Chr7:43927046-43943995 (+)
C3H/HeJ MGP_C3HHeJ_G0031877
protein coding gene Chr7:45625066-45643279 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032653
protein coding gene Chr7:47009552-47025617 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029667
protein coding gene Chr7:46514645-46528101 (+)
CAST/EiJ MGP_CASTEiJ_G0031205
protein coding gene Chr7:37009056-37026348 (+)
CBA/J MGP_CBAJ_G0031841
protein coding gene Chr7:48553204-48576824 (+)
DBA/2J MGP_DBA2J_G0031999
protein coding gene Chr7:43604479-43618367 (+)
FVB/NJ MGP_FVBNJ_G0031950
protein coding gene Chr7:43347075-43364892 (+)
LP/J MGP_LPJ_G0032077
protein coding gene Chr7:45434914-45451118 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031987
protein coding gene Chr7:47284638-47303650 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032669
protein coding gene Chr7:44355704-44372821 (+)
PWK/PhJ MGP_PWKPhJ_G0030928
protein coding gene Chr7:36952458-36968802 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030765
protein coding gene Chr7:32360595-32377779 (+)
WSB/EiJ MGP_WSBEiJ_G0031322
protein coding gene Chr7:44817856-44838501 (+)



Homology
more
  • Human Ortholog
    NAPSA, napsin A aspartic peptidase
  • Vertebrate Orthologs
    7
  • Human Ortholog
    NAPSA, napsin A aspartic peptidase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    KAP, Kdap, NAP1, NAPA, SNAPA
  • Links
    NCBI Gene ID: 9476
    neXtProt AC: NX_O96009
    UniProt: O96009

  • Chr Location
    19q13.33; chr19:50358472-50369331 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 16541 NCBI Gene Model | MGI Sequence Detail 14402 C57BL/6J ±  kb
transcript NM_008437 RefSeq | MGI Sequence Detail 1479 Not Specified  
polypeptide O09043 UniProt | EBI | MGI Sequence Detail 419 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 11
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-38410
References
more
  • Summaries
    All 44
    Developmental Gene Expression 15
    Gene Ontology 6
    Phenotypes 2
  • Earliest
    J:38131 Mori K, et al., Molecular cloning of a novel mouse aspartic protease-like protein that is expressed abundantly in the kidney. FEBS Lett. 1997 Jan 20;401(2-3):218-22
  • Latest
    J:213127 Jakus Z, et al., Lymphatic function is required prenatally for lung inflation at birth. J Exp Med. 2014 May 5;211(5):815-26

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/13/2018
MGI 6.13
The Jackson Laboratory