Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Musk

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MUSK
- Mouse genes Musk
- Rat genes Musk
- Zfish genes musk
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Musk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	musk	IPI	UniProtKB:Q5J1R9	Zfish	PMID:18296487\|ZFIN:ZDB-PUB-080306-18
Molecular Function	GO:0042802	identical protein binding	musk	IDA		Zfish	PMID:18296487
Molecular Function	GO:0030165	PDZ domain binding	Musk	IPI	UniProtKB:Q69ZS0	Mouse	MGI:MGI:3790051\|PMID:17576800
Molecular Function	GO:0005515	protein binding	MUSK	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	MUSK	IPI	UniProtKB:Q16543	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	MUSK	IPI	UniProtKB:Q16543	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	Musk	IPI	UniProtKB:Q61239	Mouse	MGI:MGI:2680892\|PMID:14622576
Molecular Function	GO:0005515	protein binding	Musk	IPI	UniProtKB:Q8VI56	Mouse	MGI:MGI:5545965\|PMID:21969364
Molecular Function	GO:0005515	protein binding	Musk	IPI	UniProtKB:P46460	Mouse	MGI:MGI:5486543\|PMID:18272689
Molecular Function	GO:0005515	protein binding	Musk	IPI	UniProtKB:Q18PE0	Mouse	MGI:MGI:4820894\|PMID:20603078
Molecular Function	GO:0005515	protein binding	Musk	IPI	UniProtKB:Q99M87-2	Mouse	MGI:MGI:3835221\|PMID:19038220
Molecular Function	GO:0005515	protein binding	Musk	IPI	UniProtKB:Q8VI56	Mouse	MGI:MGI:3834767\|PMID:18848351
Molecular Function	GO:0005515	protein binding	Musk	IPI	UniProtKB:Q18PE0	Mouse	MGI:MGI:5619467\|PMID:20371544
Molecular Function	GO:0005515	protein binding	Musk	IPI	UniProtKB:Q9QYP1	Mouse	MGI:MGI:3829843\|PMID:18957220
Molecular Function	GO:0005515	protein binding	Musk	IPI	PR:O88643	Mouse	PMID:12165471
Molecular Function	GO:0005515	protein binding	Musk	IPI	PR:P51141	Mouse	PMID:12165471
Molecular Function	GO:0005515	protein binding	Musk	IPI	PR:O35348	Mouse	PMID:20053883
Molecular Function	GO:0005515	protein binding	Musk	IPI	PR:Q80UW3	Mouse	PMID:21419809
Molecular Function	GO:0005515	protein binding	Musk	IPI	PR:Q61006	Mouse	PMID:17452444
Molecular Function	GO:0005515	protein binding	Musk	IPI	PR:Q924T7	Mouse	PMID:14678832
Molecular Function	GO:0005515	protein binding	Musk	IPI	RGD:62002	Rat	PMID:15604144\|RGD:2317103
Molecular Function	GO:0005515	protein binding	Musk	IPI	RGD:1320858	Rat	PMID:21419809\|RGD:7247588
Molecular Function	GO:0005515	protein binding	musk	IPI	UniProtKB:Q6NW92	Zfish	PMID:18296487\|ZFIN:ZDB-PUB-080306-18
Molecular Function	GO:0005515	protein binding	musk	IPI	UniProtKB:Q7SX76	Zfish	PMID:18296487\|ZFIN:ZDB-PUB-080306-18
Molecular Function	GO:0005515	protein binding	musk	IPI	UniProtKB:Q7ZU88	Zfish	PMID:18296487\|ZFIN:ZDB-PUB-080306-18
Molecular Function	GO:0005515	protein binding	musk	IPI	UniProtKB:Q90YM1	Zfish	PMID:18296487\|ZFIN:ZDB-PUB-080306-18
Molecular Function	GO:0005515	protein binding	musk	IPI	UniProtKB:Q90YM1	Zfish	PMID:18296487
Molecular Function	GO:0005515	protein binding	musk	IPI	UniProtKB:Q6NW92	Zfish	PMID:18296487
Molecular Function	GO:0005515	protein binding	musk	IPI	UniProtKB:A4JYL6	Zfish	PMID:18296487
Molecular Function	GO:0005515	protein binding	musk	IPI	UniProtKB:Q7ZU88	Zfish	PMID:18296487
Molecular Function	GO:0005515	protein binding	musk	IPI	UniProtKB:Q7SX76	Zfish	PMID:18296487
Molecular Function	GO:0019901	protein kinase binding	Musk	IPI	RGD:1347139	Rat	PMID:16818610\|RGD:2317096
Molecular Function	GO:0004713	protein tyrosine kinase activity	Musk	IDA		Rat	PMID:12220490\|RGD:2317112
Molecular Function	GO:0004713	protein tyrosine kinase activity	Musk	IDA		Rat	PMID:20603078\|RGD:8553282
Cellular Component	GO:0042995	cell projection	Musk	IDA		Rat	PMID:16899069\|RGD:2317091
Cellular Component	GO:0009897	external side of plasma membrane	Musk	IDA		Rat	PMID:17011580\|RGD:2317087
Cellular Component	GO:0016020	membrane	Musk	IDA		Mouse	PMID:20053883
Cellular Component	GO:0031594	neuromuscular junction	Musk	IDA		Mouse	MGI:MGI:3835221\|PMID:19038220
Cellular Component	GO:0031594	neuromuscular junction	Musk	IDA		Mouse	MGI:MGI:3829843\|PMID:18957220
Cellular Component	GO:0031594	neuromuscular junction	Musk	IDA		Mouse	PMID:20053883
Cellular Component	GO:0031594	neuromuscular junction	Musk	IDA		Mouse	PMID:17119023
Cellular Component	GO:0031594	neuromuscular junction	Musk	IDA		Rat	PMID:9698449\|RGD:2317114
Cellular Component	GO:0005886	plasma membrane	Musk	IDA		Mouse	MGI:MGI:3835221\|PMID:19038220
Cellular Component	GO:0005886	plasma membrane	Musk	IDA		Mouse	PMID:14678832
Cellular Component	GO:0005886	plasma membrane	musk	IMP	ZFIN:ZDB-GENO-070410-2	Zfish	PMID:17284594\|ZFIN:ZDB-PUB-070212-37
Cellular Component	GO:0045211	postsynaptic membrane	Musk	IDA		Mouse	MGI:MGI:3835221\|PMID:19038220
Cellular Component	GO:0045211	postsynaptic membrane	musk	IDA		Zfish	PMID:15543140
Cellular Component	GO:0043235	receptor complex	MUSK	IDA		Human	PMID:23382219
Cellular Component	GO:0045202	synapse	Musk	IDA		Mouse	PMID:20053883
Biological Process	GO:0007411	axon guidance	musk	IMP	ZFIN:ZDB-MRPHLNO-091209-1	Zfish	PMID:29462491
Biological Process	GO:0090102	cochlea development	Musk	IEP		Rat	PMID:18420419\|RGD:2317082
Biological Process	GO:0060291	long-term synaptic potentiation	Musk	IMP		Rat	PMID:16870737\|RGD:2317092
Biological Process	GO:0007613	memory	Musk	IMP		Rat	PMID:16870737\|RGD:2317092
Biological Process	GO:0097049	motor neuron apoptotic process	Musk	IMP	MGI:MGI:1929066	Mouse	PMID:11312299
Biological Process	GO:0008045	motor neuron axon guidance	musk	IMP	ZFIN:ZDB-GENO-050216-7	Zfish	PMID:15543140
Biological Process	GO:0008045	motor neuron axon guidance	musk	IMP	ZFIN:ZDB-GENO-020114-1	Zfish	PMID:15543140
Biological Process	GO:0008045	motor neuron axon guidance	musk	IMP	ZFIN:ZDB-GENO-980202-124	Zfish	PMID:9007258
Biological Process	GO:0030517	negative regulation of axon extension	musk	IMP		Zfish	PMID:16110513
Biological Process	GO:0010629	negative regulation of gene expression	Musk	IDA		Rat	PMID:15604144\|RGD:2317103
Biological Process	GO:0007528	neuromuscular junction development	MUSK	IDA		Human	PMID:25537362
Biological Process	GO:0007528	neuromuscular junction development	Musk	IGI	MGI:MGI:94941	Mouse	PMID:12165471
Biological Process	GO:0007528	neuromuscular junction development	Musk	IGI	MGI:MGI:87961	Mouse	PMID:12165471
Biological Process	GO:0007528	neuromuscular junction development	Musk	IGI	MGI:MGI:3584043	Mouse	PMID:16794080
Biological Process	GO:0007528	neuromuscular junction development	Musk	IEP		Rat	PMID:7546737\|RGD:633425
Biological Process	GO:0010628	positive regulation of gene expression	Musk	IMP		Rat	PMID:16870737\|RGD:2317092
Biological Process	GO:2000673	positive regulation of motor neuron apoptotic process	Musk	IMP	MGI:MGI:1929066	Mouse	PMID:11312299
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Musk	IDA		Rat	PMID:18436384\|RGD:2317081
Biological Process	GO:2000541	positive regulation of protein geranylgeranylation	Musk	IMP		Mouse	MGI:MGI:2680892\|PMID:14622576
Biological Process	GO:0001934	positive regulation of protein phosphorylation	MUSK	IMP		Human	PMID:25537362
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Musk	IMP		Mouse	MGI:MGI:2680892\|PMID:14622576
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Musk	IMP		Rat	PMID:16870737\|RGD:2317092
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Musk	IDA		Rat	PMID:18436384\|RGD:2317081
Biological Process	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering	Musk	IMP		Mouse	MGI:MGI:3829843\|PMID:18957220
Biological Process	GO:0045887	positive regulation of synaptic assembly at neuromuscular junction	Musk	IMP		Rat	PMID:14749715\|RGD:2317108
Biological Process	GO:0032224	positive regulation of synaptic transmission, cholinergic	Musk	IMP		Rat	PMID:16870737\|RGD:2317092
Biological Process	GO:0046777	protein autophosphorylation	Musk	IDA		Rat	PMID:16818610\|RGD:2317096
Biological Process	GO:0043113	receptor clustering	Musk	IGI	MGI:MGI:94941	Mouse	PMID:12165471
Biological Process	GO:0043113	receptor clustering	Musk	IMP	MGI:MGI:1929066	Mouse	PMID:11395002
Biological Process	GO:0043113	receptor clustering	Musk	IGI	MGI:MGI:3584043	Mouse	PMID:16794080
Biological Process	GO:0043113	receptor clustering	Musk	IGI	MGI:MGI:87961	Mouse	PMID:12165471
Biological Process	GO:0043113	receptor clustering	Musk	IMP		Rat	PMID:16818610\|RGD:2317096
Biological Process	GO:0043113	receptor clustering	musk	IMP	ZFIN:ZDB-GENO-070410-2	Zfish	PMID:17284594
Biological Process	GO:0043113	receptor clustering	musk	IMP	ZFIN:ZDB-GENO-070410-1	Zfish	PMID:17284594
Biological Process	GO:0043113	receptor clustering	musk	IMP	ZFIN:ZDB-MRPHLNO-050218-2	Zfish	PMID:17284594
Biological Process	GO:0006355	regulation of DNA-templated transcription	Musk	IMP	MGI:MGI:1929066	Mouse	PMID:10320756
Biological Process	GO:0008582	regulation of synaptic assembly at neuromuscular junction	Musk	IMP	MGI:MGI:1929066	Mouse	PMID:8653786
Biological Process	GO:0048678	response to axon injury	Musk	IEP		Rat	PMID:9698449\|RGD:2317114
Biological Process	GO:0051602	response to electrical stimulus	Musk	IMP		Rat	PMID:16870737\|RGD:2317092
Biological Process	GO:0014850	response to muscle activity	Musk	IEP		Rat	PMID:9698449\|RGD:2317114
Biological Process	GO:0060041	retina development in camera-type eye	Musk	IEP		Rat	PMID:16899069\|RGD:2317091
Biological Process	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	Musk	IMP		Mouse	MGI:MGI:2663717\|PMID:11323662
Biological Process	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	musk	IMP	ZFIN:ZDB-GENO-070410-1	Zfish	PMID:19285469
Biological Process	GO:0051124	synaptic assembly at neuromuscular junction	musk	IMP	ZFIN:ZDB-GENO-070410-1	Zfish	PMID:17284594
Biological Process	GO:0051124	synaptic assembly at neuromuscular junction	musk	IMP	ZFIN:ZDB-MRPHLNO-050218-2	Zfish	PMID:17284594
Biological Process	GO:0051124	synaptic assembly at neuromuscular junction	musk	IMP	ZFIN:ZDB-GENO-070410-2	Zfish	PMID:17284594

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.