Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MTMR2
  • Mouse genes Mtmr2
  • Rat genes Mtmr2
  • Zfish genes mtmr2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mtmr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Mtmr2	IPI	PR:Q9Z2D1	Mouse	PMID:16399794
Molecular Function	GO:0052866	phosphatidylinositol phosphate phosphatase activity	Mtmr2	IMP	MGI:MGI:3513454	Mouse	PMID:22028665
Molecular Function	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	MTMR2	IDA		Human	PMID:12668758
Molecular Function	GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	MTMR2	IDA		Human	PMID:12668758
Molecular Function	GO:0005515	protein binding	MTMR2	IPI	UniProtKB:P07196	Human	PMID:12837694
Molecular Function	GO:0005515	protein binding	MTMR2	IPI	UniProtKB:Q9C0I1	Human	PMID:12847286
Molecular Function	GO:0005515	protein binding	MTMR2	IPI	UniProtKB:Q86WG5	Human	PMID:15998640
Molecular Function	GO:0005515	protein binding	MTMR2	IPI	UniProtKB:Q9C0I1	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	Mtmr2	IPI	PR:E9PXF8	Mouse	PMID:16399794
Molecular Function	GO:0005515	protein binding	Mtmr2	IPI	UniProtKB:P31016	Rat	PMID:20410104|RGD:8553482
Molecular Function	GO:0005515	protein binding	Mtmr2	IPI	UniProtKB:Q62936	Rat	PMID:20410104|RGD:8553482
Molecular Function	GO:0005515	protein binding	Mtmr2	IPI	UniProtKB:Q63622	Rat	PMID:20410104|RGD:8553482
Cellular Component	GO:0030424	axon	Mtmr2	IDA		Rat	PMID:20410104|RGD:8553482
Cellular Component	GO:0005737	cytoplasm	MTMR2	IDA		Human	PMID:12837694
Cellular Component	GO:0005737	cytoplasm	Mtmr2	IDA		Mouse	PMID:12837694
Cellular Component	GO:0005737	cytoplasm	Mtmr2	IDA		Mouse	PMID:16399794
Cellular Component	GO:0005829	cytosol	MTMR2	IDA		Human	PMID:12668758
Cellular Component	GO:0005829	cytosol	Mtmr2	IDA		Rat	PMID:20410104|RGD:8553482
Cellular Component	GO:0030425	dendrite	Mtmr2	IDA		Rat	PMID:20410104|RGD:8553482
Cellular Component	GO:0043197	dendritic spine	Mtmr2	IDA		Rat	PMID:20410104|RGD:8553482
Cellular Component	GO:0070062	extracellular exosome	MTMR2	HDA		Human	PMID:18570454
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MTMR2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MTMR2	IDA		Human	PMID:12837694
Cellular Component	GO:0005634	nucleus	MTMR2	IDA		Human	PMID:16787938
Cellular Component	GO:0014069	postsynaptic density	Mtmr2	IDA		Rat	PMID:20410104|RGD:8553482
Cellular Component	GO:0097060	synaptic membrane	Mtmr2	IDA		Rat	PMID:20410104|RGD:8553482
Cellular Component	GO:0008021	synaptic vesicle	Mtmr2	IDA		Rat	PMID:20410104|RGD:8553482
Cellular Component	GO:0005774	vacuolar membrane	Mtmr2	IDA		Mouse	PMID:16399794
Biological Process	GO:0097062	dendritic spine maintenance	Mtmr2	IMP		Rat	PMID:20410104|RGD:8553482
Biological Process	GO:0016311	dephosphorylation	Mtmr2	IDA		Mouse	PMID:16399794
Biological Process	GO:0032288	myelin assembly	Mtmr2	IGI	MGI:MGI:1335106	Mouse	PMID:22028665
Biological Process	GO:0032288	myelin assembly	Mtmr2	IMP	MGI:MGI:3513454	Mouse	PMID:22028665
Biological Process	GO:0032288	myelin assembly	Mtmr2	IGI	MGI:MGI:2143585	Mouse	PMID:22028665
Biological Process	GO:0042552	myelination	Mtmr2	IGI	MGI:MGI:2143585	Mouse	PMID:22028665
Biological Process	GO:0045806	negative regulation of endocytosis	Mtmr2	IMP		Rat	PMID:20410104|RGD:8553482
Biological Process	GO:0090394	negative regulation of excitatory postsynaptic potential	Mtmr2	IMP		Rat	PMID:20410104|RGD:8553482
Biological Process	GO:0031642	negative regulation of myelination	Mtmr2	IMP	MGI:MGI:3513454	Mouse	PMID:19587293
Biological Process	GO:0031642	negative regulation of myelination	Mtmr2	IGI	MGI:MGI:2143585	Mouse	PMID:22028665
Biological Process	GO:2000645	negative regulation of receptor catabolic process	Mtmr2	IMP		Rat	PMID:20410104|RGD:8553482
Biological Process	GO:0002091	negative regulation of receptor internalization	Mtmr2	IMP		Rat	PMID:20410104|RGD:8553482
Biological Process	GO:0048666	neuron development	Mtmr2	IGI	MGI:MGI:2143585	Mouse	PMID:22028665
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	MTMR2	IDA		Human	PMID:12668758
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	Mtmr2	IDA		Mouse	PMID:16399794
Biological Process	GO:0046488	phosphatidylinositol metabolic process	Mtmr2	IMP	MGI:MGI:3513454	Mouse	PMID:22028665
Biological Process	GO:2000643	positive regulation of early endosome to late endosome transport	Mtmr2	IMP		Rat	PMID:20410104|RGD:8553482
Biological Process	GO:0060304	regulation of phosphatidylinositol dephosphorylation	MTMR2	IDA		Human	PMID:16787938

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern