Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MRTFB
  • Mouse genes Mrtfb
  • Rat genes
  • Zfish genes mrtfba,mrtfbb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mrtfb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Mrtfb	IDA		Mouse	PMID:15798203
Molecular Function	GO:0045296	cadherin binding	MRTFB	HDA		Human	PMID:25468996
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Mrtfb	IDA		Mouse	PMID:17991879
Molecular Function	GO:0005515	protein binding	MRTFB	IPI	UniProtKB:P11831	Human	PMID:12397177
Molecular Function	GO:0005515	protein binding	MRTFB	IPI	UniProtKB:P11831	Human	PMID:14565952
Molecular Function	GO:0005515	protein binding	MRTFB	IPI	UniProtKB:Q969V6	Human	PMID:14565952
Molecular Function	GO:0005515	protein binding	MRTFB	IPI	UniProtKB:O00629	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Mrtfb	IPI	UniProtKB:Q9JM73	Mouse	MGI:MGI:2663933|PMID:12397177
Molecular Function	GO:0005515	protein binding	Mrtfb	IPI	PR:Q6PCM1	Mouse	PMID:17991879
Molecular Function	GO:0003713	transcription coactivator activity	MRTFB	IDA		Human	PMID:14565952
Molecular Function	GO:0003713	transcription coactivator activity	MRTFB	IGI	UniProtKB:P11831	Human	PMID:23764775
Molecular Function	GO:0003713	transcription coactivator activity	Mrtfb	IDA		Mouse	MGI:MGI:2663933|PMID:12397177
Cellular Component	GO:0005737	cytoplasm	Mrtfb	IDA		Mouse	PMID:15798203
Biological Process	GO:0030036	actin cytoskeleton organization	Mrtfb	IGI	MGI:MGI:2384495	Mouse	PMID:20534669
Biological Process	GO:0048514	blood vessel morphogenesis	Mrtfb	IMP	MGI:MGI:3608959	Mouse	PMID:16204380
Biological Process	GO:0048738	cardiac muscle tissue development	Mrtfb	IMP	MGI:MGI:3587937	Mouse	PMID:17183527
Biological Process	GO:0048568	embryonic organ development	Mrtfb	IMP	MGI:MGI:3587937	Mouse	PMID:17183527
Biological Process	GO:0030900	forebrain development	Mrtfb	IGI	MGI:MGI:2384495	Mouse	PMID:20534669
Biological Process	GO:0010467	gene expression	Mrtfb	IMP	MGI:MGI:3587937	Mouse	PMID:17183527
Biological Process	GO:0007507	heart development	Mrtfb	IMP	MGI:MGI:3608959	Mouse	PMID:16204380
Biological Process	GO:0003007	heart morphogenesis	Mrtfb	IMP	MGI:MGI:3587937	Mouse	PMID:17183527
Biological Process	GO:0001701	in utero embryonic development	Mrtfb	IMP	MGI:MGI:3587937	Mouse	PMID:17183527
Biological Process	GO:0001889	liver development	Mrtfb	IMP	MGI:MGI:3587937	Mouse	PMID:17183527
Biological Process	GO:0001764	neuron migration	Mrtfb	IGI	MGI:MGI:2384495	Mouse	PMID:20534669
Biological Process	GO:0031175	neuron projection development	Mrtfb	IGI	MGI:MGI:2384495	Mouse	PMID:20534669
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Mrtfb	IDA		Mouse	PMID:15798203
Biological Process	GO:1902895	positive regulation of miRNA transcription	MRTFB	IGI	UniProtKB:P11831	Human	PMID:23764775
Biological Process	GO:0045844	positive regulation of striated muscle tissue development	MRTFB	IDA		Human	PMID:14565952
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MRTFB	IDA		Human	PMID:14565952
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mrtfb	IDA		Mouse	MGI:MGI:2663933|PMID:12397177
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mrtfb	IDA		Mouse	PMID:18945672
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mrtfb	IDA		Mouse	PMID:17991879
Biological Process	GO:0010468	regulation of gene expression	Mrtfb	IMP	MGI:MGI:3587937	Mouse	PMID:17183527
Biological Process	GO:0035886	vascular associated smooth muscle cell differentiation	Mrtfb	IMP	MGI:MGI:3608959	Mouse	PMID:16204380

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern