Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MPIG6B
  • Mouse genes Mpig6b
  • Rat genes Mpig6b
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mpig6b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MPIG6B	IPI	UniProtKB:P29350|UniProtKB:Q06124	Human	PMID:23112346
Molecular Function	GO:0005515	protein binding	Mpig6b	IPI	UniProtKB:P29351|UniProtKB:P35235	Mouse	MGI:MGI:5512895|PMID:23112346
Cellular Component	GO:0005829	cytosol	MPIG6B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	MPIG6B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	MPIG6B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MPIG6B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	MPIG6B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	MPIG6B	IDA		Human	PMID:11544253
Biological Process	GO:0007596	blood coagulation	Mpig6b	IMP	MGI:MGI:2675830	Mouse	PMID:23112346
Biological Process	GO:0030218	erythrocyte differentiation	MPIG6B	IMP		Human	PMID:27743390
Biological Process	GO:0007229	integrin-mediated signaling pathway	Mpig6b	IMP	MGI:MGI:2675830	Mouse	PMID:23112346
Biological Process	GO:0035855	megakaryocyte development	Mpig6b	IMP	MGI:MGI:2675830	Mouse	PMID:23112346
Biological Process	GO:0030219	megakaryocyte differentiation	MPIG6B	IMP		Human	PMID:27743390
Biological Process	GO:0009968	negative regulation of signal transduction	MPIG6B	IDA		Human	PMID:18955485
Biological Process	GO:0030220	platelet formation	Mpig6b	IMP	MGI:MGI:2675830	Mouse	PMID:23112346
Biological Process	GO:0030220	platelet formation	Mpig6b	IGI	MGI:MGI:99511	Mouse	PMID:23509158
Biological Process	GO:0030220	platelet formation	Mpig6b	IGI	MGI:MGI:96055	Mouse	PMID:23509158
Biological Process	GO:0030220	platelet formation	Mpig6b	IGI	MGI:MGI:1913287	Mouse	PMID:23112346

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern