| GO term: | megakaryocyte development |
| Synonym: | megakaryocyte cell development |
| GO id: | GO:0035855 |
| Definition: | The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow. |
| Number of paths to term: | 39 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
biological_processcellular processsingle-organism cellular processcellular developmental processcell developmentmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processcellular processsingle-organism cellular processcellular developmental processcell differentiationcell developmentmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processcellular processsingle-organism cellular processcellular developmental processcell differentiationmyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processcellular processsingle-organism cellular processcellular developmental processcell differentiationmyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processdevelopmental processanatomical structure developmentcell developmentmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processdevelopmental processanatomical structure developmentorgan developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processdevelopmental processanatomical structure developmentorgan developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processdevelopmental processanatomical structure developmentsystem developmentimmune system developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processdevelopmental processanatomical structure developmentsystem developmentimmune system developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processdevelopmental processanatomical structure developmentsystem developmentorgan developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processdevelopmental processanatomical structure developmentsystem developmentorgan developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processdevelopmental processcellular developmental processcell developmentmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processdevelopmental processcellular developmental processcell differentiationcell developmentmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processdevelopmental processcellular developmental processcell differentiationmyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processdevelopmental processcellular developmental processcell differentiationmyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processdevelopmental processmulticellular organismal developmentsystem developmentimmune system developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processdevelopmental processmulticellular organismal developmentsystem developmentimmune system developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processdevelopmental processmulticellular organismal developmentsystem developmentorgan developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processdevelopmental processmulticellular organismal developmentsystem developmentorgan developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processdevelopmental processsingle-organism developmental processcell developmentmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processdevelopmental processsingle-organism developmental processhematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processdevelopmental processsingle-organism developmental processhematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processimmune system processimmune system developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processimmune system processimmune system developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processmulticellular organismal processsingle-multicellular organism processmulticellular organismal developmentsystem developmentimmune system developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processmulticellular organismal processsingle-multicellular organism processmulticellular organismal developmentsystem developmentimmune system developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processmulticellular organismal processsingle-multicellular organism processmulticellular organismal developmentsystem developmentorgan developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processmulticellular organismal processsingle-multicellular organism processmulticellular organismal developmentsystem developmentorgan developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processsingle-organism processsingle-multicellular organism processmulticellular organismal developmentsystem developmentimmune system developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processsingle-organism processsingle-multicellular organism processmulticellular organismal developmentsystem developmentimmune system developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processsingle-organism processsingle-multicellular organism processmulticellular organismal developmentsystem developmentorgan developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processsingle-organism processsingle-multicellular organism processmulticellular organismal developmentsystem developmentorgan developmenthematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processsingle-organism processsingle-organism cellular processcellular developmental processcell developmentmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processsingle-organism processsingle-organism cellular processcellular developmental processcell differentiationcell developmentmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processsingle-organism processsingle-organism cellular processcellular developmental processcell differentiationmyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processsingle-organism processsingle-organism cellular processcellular developmental processcell differentiationmyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processsingle-organism processsingle-organism developmental processcell developmentmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)biological_processsingle-organism processsingle-organism developmental processhematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmegakaryocyte differentiationmegakaryocyte development [GO:0035855] (12 genes, 12 annotations)negative regulation of megakaryocyte differentiationpositive regulation of megakaryocyte differentiationregulation of megakaryocyte differentiation +biological_processsingle-organism processsingle-organism developmental processhematopoietic or lymphoid organ developmenthemopoiesismyeloid cell differentiationmyeloid cell developmenterythrocyte development +megakaryocyte development [GO:0035855] (12 genes, 12 annotations)Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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