Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MMEL1
  • Mouse genes Mmel1
  • Rat genes Mmel1
  • Zfish genes mmel1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mmel1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004175	endopeptidase activity	MMEL1	IDA		Human	PMID:18539150
Molecular Function	GO:0004222	metalloendopeptidase activity	Mmel1	IDA		Rat	PMID:11964170|RGD:2314417
Molecular Function	GO:0008270	zinc ion binding	Mmel1	IDA		Rat	PMID:15294904|RGD:2314418
Cellular Component	GO:0005783	endoplasmic reticulum	Mmel1	IDA		Mouse	PMID:10542292
Cellular Component	GO:0005615	extracellular space	MMEL1	IDA		Human	PMID:18539150
Cellular Component	GO:0005615	extracellular space	Mmel1	IDA		Rat	PMID:11964170|RGD:2314417
Cellular Component	GO:0005794	Golgi apparatus	Mmel1	IDA		Mouse	PMID:10542292
Cellular Component	GO:0016020	membrane	MMEL1	IDA		Human	PMID:18539150
Cellular Component	GO:0016020	membrane	Mmel1	IDA		Rat	PMID:11964170|RGD:2314417
Biological Process	GO:0006508	proteolysis	MMEL1	IDA		Human	PMID:18539150

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern