Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Mkks

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MKKS
- Mouse genes Mkks
- Rat genes Mkks
- Zfish genes mkks
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mkks

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:Q9BUN5	Human	PMID:16327777
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:Q9NRI5	Human	PMID:18762586
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:Q6ZW61	Human	PMID:20080638
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:Q9BXC9	Human	PMID:20080638
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:O15078	Human	PMID:22446187
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:Q6ZW61	Human	PMID:22500027
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:Q9BXC9	Human	PMID:22500027
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:Q6ZW61	Human	PMID:26900326
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:Q6ZW61	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:Q92922	Human	PMID:28753627
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:O96006	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:Q01850	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MKKS	IPI	UniProtKB:Q9Y238	Human	PMID:33144677
Molecular Function	GO:0005515	protein binding	mkks	IPI	ZFIN:ZDB-GENE-080514-3	Zfish	PMID:28753627
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	MKKS	IPI	UniProtKB:Q99496	Human	PMID:22302990
Cellular Component	GO:0005813	centrosome	MKKS	IDA		Human	GO_REF:0000052
Cellular Component	GO:0036064	ciliary basal body	Mkks	IDA		Mouse	PMID:22446187
Cellular Component	GO:0005737	cytoplasm	MKKS	IDA		Human	PMID:28753627
Cellular Component	GO:0005737	cytoplasm	mkks	IDA		Zfish	PMID:28753627
Cellular Component	GO:1902636	kinociliary basal body	Mkks	IDA		Mouse	PMID:22446187
Cellular Component	GO:0031514	motile cilium	Mkks	IMP		Mouse	MGI:MGI:3776933\|PMID:18299575
Cellular Component	GO:0005634	nucleus	MKKS	IDA		Human	PMID:28753627
Cellular Component	GO:0005634	nucleus	mkks	IDA		Zfish	PMID:28753627
Biological Process	GO:0014824	artery smooth muscle contraction	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:20852044
Biological Process	GO:0048854	brain morphogenesis	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:18032602
Biological Process	GO:0043010	camera-type eye development	mkks	IGI	ZFIN:ZDB-MRPHLNO-060209-5,ZFIN:ZDB-MRPHLNO-080428-2	Zfish	PMID:22446187
Biological Process	GO:0051216	cartilage development	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:19195025
Biological Process	GO:0021987	cerebral cortex development	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:18032602
Biological Process	GO:0051131	chaperone-mediated protein complex assembly	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:20080638
Biological Process	GO:0060271	cilium assembly	MKKS	IMP		Human	PMID:28753627
Biological Process	GO:0060271	cilium assembly	Mkks	IMP		Mouse	MGI:MGI:3776933\|PMID:18299575
Biological Process	GO:0060271	cilium assembly	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:15772095
Biological Process	GO:0060271	cilium assembly	mkks	IMP	ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:16399798
Biological Process	GO:0060026	convergent extension	mkks	IMP	ZFIN:ZDB-MRPHLNO-060126-1	Zfish	PMID:17906624
Biological Process	GO:0060026	convergent extension	mkks	IGI	ZFIN:ZDB-GENO-080222-4,ZFIN:ZDB-MRPHLNO-060126-1	Zfish	PMID:17906624
Biological Process	GO:0060026	convergent extension	mkks	IGI	ZFIN:ZDB-GENO-080222-3,ZFIN:ZDB-MRPHLNO-060126-1	Zfish	PMID:17906624
Biological Process	GO:0060027	convergent extension involved in gastrulation	mkks	IMP		Zfish	PMID:17160889
Biological Process	GO:0060027	convergent extension involved in gastrulation	mkks	IMP	ZFIN:ZDB-MRPHLNO-060126-1	Zfish	PMID:16582908
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	Mkks	IMP	MGI:MGI:3608879	Mouse	PMID:16170314
Biological Process	GO:0007368	determination of left/right symmetry	mkks	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:18381349
Biological Process	GO:0007368	determination of left/right symmetry	mkks	IGI	ZFIN:ZDB-MRPHLNO-060209-5,ZFIN:ZDB-MRPHLNO-081027-1	Zfish	PMID:18381349
Biological Process	GO:0007368	determination of left/right symmetry	mkks	IMP	ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:16399798
Biological Process	GO:0060324	face development	Mkks	IMP	MGI:MGI:3608879	Mouse	PMID:18443298
Biological Process	GO:0045444	fat cell differentiation	Mkks	IEP		Mouse	MGI:MGI:3794016\|PMID:17379567
Biological Process	GO:0007369	gastrulation	mkks	IMP	ZFIN:ZDB-MRPHLNO-060126-1	Zfish	PMID:20498079
Biological Process	GO:0007369	gastrulation	mkks	IMP	ZFIN:ZDB-MRPHLNO-140821-1	Zfish	PMID:20498079
Biological Process	GO:0010467	gene expression	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:19150989
Biological Process	GO:0010467	gene expression	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:18317593
Biological Process	GO:0001947	heart looping	mkks	IMP	ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:16399798
Biological Process	GO:0021766	hippocampus development	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:18032602
Biological Process	GO:0048839	inner ear development	mkks	IGI	ZFIN:ZDB-MRPHLNO-060209-5,ZFIN:ZDB-MRPHLNO-080428-2	Zfish	PMID:22446187
Biological Process	GO:0046907	intracellular transport	mkks	IMP	ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:16399798
Biological Process	GO:0070121	Kupffer's vesicle development	mkks	IGI	ZFIN:ZDB-MRPHLNO-060209-5,ZFIN:ZDB-MRPHLNO-081027-1	Zfish	PMID:18381349
Biological Process	GO:0070121	Kupffer's vesicle development	mkks	IMP	ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:16399798
Biological Process	GO:0070121	Kupffer's vesicle development	mkks	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:18381349
Biological Process	GO:0033210	leptin-mediated signaling pathway	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:19150989
Biological Process	GO:0032402	melanosome transport	mkks	IMP	ZFIN:ZDB-MRPHLNO-060320-9	Zfish	PMID:28753627
Biological Process	GO:0032402	melanosome transport	mkks	IGI	ZFIN:ZDB-MRPHLNO-060209-3,ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:18381349
Biological Process	GO:0032402	melanosome transport	mkks	IMP	ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:16399798
Biological Process	GO:0032402	melanosome transport	mkks	IGI	ZFIN:ZDB-MRPHLNO-060209-5,ZFIN:ZDB-MRPHLNO-081027-1	Zfish	PMID:18381349
Biological Process	GO:0030837	negative regulation of actin filament polymerization	Mkks	IMP		Mouse	PMID:23716571
Biological Process	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway	Mkks	IMP		Mouse	MGI:MGI:3836843\|PMID:19150989
Biological Process	GO:0045776	negative regulation of blood pressure	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:18317593
Biological Process	GO:0010629	negative regulation of gene expression	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:18317593
Biological Process	GO:0010629	negative regulation of gene expression	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:19150989
Biological Process	GO:0034260	negative regulation of GTPase activity	Mkks	IMP	MGI:MGI:3608879	Mouse	PMID:23716571
Biological Process	GO:1905515	non-motile cilium assembly	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:19195025
Biological Process	GO:1905515	non-motile cilium assembly	Mkks	IMP	MGI:MGI:3608879	Mouse	PMID:16170314
Biological Process	GO:1905515	non-motile cilium assembly	Mkks	IGI	MGI:MGI:2135272	Mouse	PMID:16170314
Biological Process	GO:0045494	photoreceptor cell maintenance	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:15772095
Biological Process	GO:0045494	photoreceptor cell maintenance	Mkks	IMP	MGI:MGI:3608879	Mouse	PMID:16170314
Biological Process	GO:0051877	pigment granule aggregation in cell center	mkks	IMP	ZFIN:ZDB-MRPHLNO-060209-5	Zfish	PMID:16399798
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:18317593
Biological Process	GO:0060296	regulation of cilium beat frequency involved in ciliary motility	Mkks	IMP		Mouse	MGI:MGI:3776933\|PMID:18299575
Biological Process	GO:0051492	regulation of stress fiber assembly	Mkks	IMP	MGI:MGI:3608879	Mouse	PMID:23716571
Biological Process	GO:0044321	response to leptin	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:18317593
Biological Process	GO:0007608	sensory perception of smell	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:15772095
Biological Process	GO:0007608	sensory perception of smell	Mkks	IMP	MGI:MGI:3608879	Mouse	PMID:16170314
Biological Process	GO:0035176	social behavior	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:15772095
Biological Process	GO:0007286	spermatid development	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:15772095
Biological Process	GO:0021756	striatum development	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:18032602
Biological Process	GO:0042311	vasodilation	Mkks	IMP	MGI:MGI:3526444	Mouse	PMID:20852044

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.