Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MFHAS1
  • Mouse genes Mfhas1
  • Rat genes Mfhas1
  • Zfish genes mfhas1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mfhas1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005525	GTP binding	MFHAS1	IDA		Human	PMID:24286120
Molecular Function	GO:0005515	protein binding	MFHAS1	IPI	UniProtKB:P04049	Human	PMID:23327923
Molecular Function	GO:0005515	protein binding	MFHAS1	IPI	UniProtKB:P10809	Human	PMID:24286120
Molecular Function	GO:0005515	protein binding	MFHAS1	IPI	UniProtKB:P63151	Human	PMID:28609714
Molecular Function	GO:0005515	protein binding	MFHAS1	IPI	UniProtKB:P67775	Human	PMID:28609714
Molecular Function	GO:0051721	protein phosphatase 2A binding	MFHAS1	IDA		Human	PMID:28609714
Molecular Function	GO:0031625	ubiquitin protein ligase binding	MFHAS1	IPI	UniProtKB:O43164	Human	PMID:28471450
Cellular Component	GO:0005737	cytoplasm	MFHAS1	IDA		Human	PMID:24286120
Cellular Component	GO:0005737	cytoplasm	MFHAS1	IDA		Human	PMID:28471450
Biological Process	GO:0006952	defense response	Mfhas1	IMP		Mouse	MGI:MGI:6158883|PMID:20616063
Biological Process	GO:0030218	erythrocyte differentiation	MFHAS1	IMP		Human	PMID:23327923
Biological Process	GO:0006954	inflammatory response	MFHAS1	IMP		Human	PMID:26599367
Biological Process	GO:0006954	inflammatory response	MFHAS1	IMP		Human	PMID:28471450
Biological Process	GO:0006954	inflammatory response	MFHAS1	IMP		Human	PMID:28609714
Biological Process	GO:0006954	inflammatory response	Mfhas1	IMP		Mouse	MGI:MGI:6162316|PMID:26599367
Biological Process	GO:0045087	innate immune response	MFHAS1	IMP		Human	PMID:28471450
Biological Process	GO:0045087	innate immune response	MFHAS1	IMP		Human	PMID:28609714
Biological Process	GO:0045087	innate immune response	Mfhas1	IMP		Mouse	MGI:MGI:6162316|PMID:26599367
Biological Process	GO:0050728	negative regulation of inflammatory response	MFHAS1	IMP		Human	PMID:29168081
Biological Process	GO:0035308	negative regulation of protein dephosphorylation	MFHAS1	IMP		Human	PMID:28609714
Biological Process	GO:1900181	negative regulation of protein localization to nucleus	MFHAS1	IMP		Human	PMID:28609714
Biological Process	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	MFHAS1	IMP		Human	PMID:26599367
Biological Process	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	Mfhas1	IMP		Mouse	MGI:MGI:6162316|PMID:26599367
Biological Process	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	MFHAS1	IMP		Human	PMID:28609714
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	MFHAS1	IMP		Human	PMID:23327923
Biological Process	GO:0046330	positive regulation of JNK cascade	MFHAS1	IMP		Human	PMID:28471450
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	MFHAS1	IMP		Human	PMID:28471450
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	MFHAS1	IMP		Human	PMID:29168081
Biological Process	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	MFHAS1	IMP		Human	PMID:26599367
Biological Process	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	MFHAS1	IMP		Human	PMID:28471450
Biological Process	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	Mfhas1	IMP		Mouse	MGI:MGI:6162316|PMID:26599367
Biological Process	GO:0043030	regulation of macrophage activation	MFHAS1	IMP		Human	PMID:28471450
Biological Process	GO:0034121	regulation of toll-like receptor signaling pathway	Mfhas1	IMP		Mouse	MGI:MGI:6158883|PMID:20616063

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern