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Gene Ontology Browser
Term Detail
GO term:defense response
Synonym: antimicrobial peptide activity
Synonym: defence response
Synonym: defense/immunity protein activity
Synonym: physiological defense response
GO id:GO:0006952
Definition:Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aresponse to stress
                                is-acellular response to stress +
                                is-adefense response [GO:0006952] (1066 genes, 2135 annotations)
                                        is-abehavioral defense response +
                                        is-acellular defense response +
                                        is-aclearance of foreign intracellular DNA +
                                        is-adefense response by callose deposition +
                                        part-ofdefense response by callose deposition in cell wall
                                        is-adefense response by cell wall thickening +
                                        is-adefense response to other organism +
                                        is-adefense response to tumor cell
                                        is-ainflammatory response +
                                        is-ainnate immune response +
                                        negatively-regulatesnegative regulation of defense response +
                                        positively-regulatespositive regulation of defense response +
                                        regulatesregulation of defense response +
                                        part-ofrespiratory burst involved in defense response +
                                is-amulticellular organismal response to stress +
                                is-amuscle hypertrophy in response to stress +
                                is-aphage shock
                                regulatesregulation of response to stress +
                                is-aresponse to anoxia +
                                is-aresponse to cold +
                                is-aresponse to flooding
                                is-aresponse to fluid shear stress +
                                is-aresponse to heat +
                                is-aresponse to herbicide
                                is-aresponse to hydrostatic pressure +
                                is-aresponse to hyperoxia +
                                is-aresponse to hypoxia +
                                is-aresponse to immobilization stress +
                                is-aresponse to ischemia
                                is-aresponse to isolation stress +
                                is-aresponse to nitrosative stress +
                                is-aresponse to osmotic stress +
                                is-aresponse to oxidative stress +
                                is-aresponse to starvation +
                                is-aresponse to sterol depletion +
                                is-aresponse to topologically incorrect protein +
                                is-aresponse to water deprivation +
                                is-aresponse to wounding +
                                is-astress response to acid chemical +
                                is-astress response to metal ion +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory