About   Help   FAQ
Mfhas1 Gene Detail
Summary
  • Symbol
    Mfhas1
  • Name
    malignant fibrous histiocytoma amplified sequence 1
  • Synonyms
    2310066G09Rik, D8Ertd91e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098644
    NCBI Gene: 52065
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:35587798-35679449 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 21.16 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1219 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098644
protein coding gene Chr8:35587798-35679449 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033539
protein coding gene Chr8:34207169-34302009 (+)
A/J MGP_AJ_G0033519
protein coding gene Chr8:32831944-32930629 (+)
AKR/J MGP_AKRJ_G0033443
protein coding gene Chr8:33876920-33967154 (+)
BALB/cJ MGP_BALBcJ_G0033515
protein coding gene Chr8:32969480-33059994 (+)
C3H/HeJ MGP_C3HHeJ_G0033227
protein coding gene Chr8:34216992-34309103 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034031
protein coding gene Chr8:35481619-35584054 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030980
protein coding gene Chr8:29798402-29890279 (+)
CAST/EiJ MGP_CASTEiJ_G0032554
protein coding gene Chr8:33679222-33775929 (+)
CBA/J MGP_CBAJ_G0033205
protein coding gene Chr8:36866842-36979602 (+)
DBA/2J MGP_DBA2J_G0033358
protein coding gene Chr8:32782275-32874090 (+)
FVB/NJ MGP_FVBNJ_G0033303
protein coding gene Chr8:32444570-32534932 (+)
LP/J MGP_LPJ_G0033448
protein coding gene Chr8:34156074-34252493 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033345
protein coding gene Chr8:36316974-36417672 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034050
protein coding gene Chr8:33989403-34084770 (+)
PWK/PhJ MGP_PWKPhJ_G0032265
protein coding gene Chr8:32330181-32426647 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032096
protein coding gene Chr8:33243389-33365649 (+)
WSB/EiJ MGP_WSBEiJ_G0032670
protein coding gene Chr8:34169165-34268261 (+)



Homology
more
  • Human Ortholog
    MFHAS1, malignant fibrous histiocytoma amplified sequence 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MFHAS1, malignant fibrous histiocytoma amplified sequence 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LRRC65, MASL1, ROCO4
  • Links
    NCBI Gene ID: 9258
    neXtProt AC: NX_Q9Y4C4
    UniProt: Q9Y4C4

  • Chr Location
    8p23.1; chr8:8783354-8893621 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 3114
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MFHAS1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52065 NCBI Gene Model | MGI Sequence Detail 91652 C57BL/6J ±  kb
transcript NR_157105 RefSeq | MGI Sequence Detail 6527 C57BL/6  
polypeptide Q3V1N1 UniProt | EBI | MGI Sequence Detail 1048 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 60
    cDNA 59
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1919190
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:262346 Zhong J, et al., MFHAS1 Is Associated with Sepsis and Stimulates TLR2/NF-kappaB Signaling Pathway Following Negative Regulation. PLoS One. 2015;10(11):e0143662

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/19/2019
MGI 6.13
The Jackson Laboratory