Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MCF2L
  • Mouse genes Mcf2l
  • Rat genes Mcf2l
  • Zfish genes mcf2la,mcf2lb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mcf2l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005545	1-phosphatidylinositol binding	Mcf2l	IDA		Mouse	PMID:12637522
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Mcf2l	IDA		Mouse	PMID:12637522
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Mcf2l	IDA		Rat	PMID:7957046|RGD:729022
Molecular Function	GO:0035091	phosphatidylinositol binding	MCF2L	IDA		Human	PMID:15157669
Molecular Function	GO:0005515	protein binding	Mcf2l	IPI	UniProtKB:P60953-2	Mouse	MGI:MGI:3690137|PMID:11889037
Molecular Function	GO:0005515	protein binding	Mcf2l	IPI	UniProtKB:P60953-2	Mouse	MGI:MGI:5914385|PMID:17704816
Molecular Function	GO:0005515	protein binding	Mcf2l	IPI	PR:Q640L3	Mouse	PMID:17000758
Cellular Component	GO:0005737	cytoplasm	Mcf2l	IDA		Rat	PMID:7957046|RGD:729022
Cellular Component	GO:0005615	extracellular space	MCF2L	HDA		Human	PMID:22664934
Cellular Component	GO:0019898	extrinsic component of membrane	Mcf2l	IDA		Rat	PMID:7957046|RGD:729022
Cellular Component	GO:0030027	lamellipodium	Mcf2l	IDA		Mouse	PMID:12637522
Cellular Component	GO:0016020	membrane	Mcf2l	IDA		Mouse	PMID:12637522
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	Mcf2l	IDA		Rat	PMID:7957046|RGD:729022
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Mcf2l	IGI	MGI:MGI:1196419	Mouse	PMID:17000758
Biological Process	GO:0007266	Rho protein signal transduction	Mcf2l	IDA		Mouse	PMID:12637522

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern