Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MARCHF8
  • Mouse genes Marchf8
  • Rat genes Marchf8
  • Zfish genes marchf8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Marchf8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042289	MHC class II protein binding	Marchf8	IPI	UniProtKB:P14483	Mouse	MGI:MGI:3785681|PMID:16785530
Molecular Function	GO:0005515	protein binding	MARCHF8	IPI	UniProtKB:O14653	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARCHF8	IPI	UniProtKB:O43169	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARCHF8	IPI	UniProtKB:P36575-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARCHF8	IPI	UniProtKB:P63027	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARCHF8	IPI	UniProtKB:Q7L5A8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MARCHF8	IPI	UniProtKB:Q9P0S9	Human	PMID:32296183
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Marchf8	IDA		Mouse	PMID:16785530
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	MARCHF8	IDA		Human	PMID:14722266
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	MARCHF8	IDA		Human	PMID:19117940
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Marchf8	IDA		Mouse	MGI:MGI:3785681|PMID:16785530
Cellular Component	GO:0005768	endosome	MARCHF8	IDA		Human	PMID:14722266
Cellular Component	GO:0005764	lysosome	MARCHF8	IDA		Human	PMID:14722266
Biological Process	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	Marchf8	IDA		Mouse	MGI:MGI:3785681|PMID:16785530
Biological Process	GO:0045347	negative regulation of MHC class II biosynthetic process	Marchf8	IDA		Mouse	MGI:MGI:3785681|PMID:16785530
Biological Process	GO:0000209	protein polyubiquitination	MARCHF8	IDA		Human	PMID:19117940
Biological Process	GO:0016567	protein ubiquitination	Marchf8	IDA		Mouse	MGI:MGI:3785681|PMID:16785530
Biological Process	GO:0016567	protein ubiquitination	marchf8	IDA		Zfish	PMID:24752240

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern