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March8 Gene Detail
Summary
  • Symbol
    March8
  • Name
    membrane-associated ring finger (C3HC4) 8
  • Synonyms
    1300017E09Rik, Mir
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919029
    NCBI Gene: 71779
Location & Maps
more
  • Sequence Map
    Chr6:116338024-116409540 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      71517 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 53.78 cM, cytoband F1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    MARCH8, membrane associated ring-CH-type finger 8
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MARCH8, membrane associated ring-CH-type finger 8
    Orthology source: HGNC, HomoloGene
  • Synonyms
    c-MIR, CMIR, MARCH-VIII, MIR, RNF178
  • Links
    NCBI Gene ID: 220972
    neXtProt AC: NX_Q5T0T0

  • Chr Location
    10q11.21; chr10:45454585-45594906 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016676 VEGA Gene Model | MGI Sequence Detail 71517 C57BL/6J ±  kb
transcript OTTMUST00000040381 VEGA | MGI Sequence Detail 2102 Not Applicable  
polypeptide OTTMUSP00000073495 VEGA | MGI Sequence Detail 568 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    455 from dbSNP Build 142
Protein
Information
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  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000010182 E3 ubiquitin-protein ligase MARCH8
  • EC
  • InterPro Domains
    IPR033275 E3 ubiquitin-protein ligase MARCH-like
    IPR011016 Zinc finger, RING-CH-type
    IPR013083 Zinc finger, RING/FYVE/PHD-type
Molecular
Reagents
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  • All nucleic 146
    cDNA 146

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory