Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Mapk8ip3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MAPK8IP3
- Mouse genes Mapk8ip3
- Rat genes Mapk8ip3
- Zfish genes mapk8ip3
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mapk8ip3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140312	cargo adaptor activity	mapk8ip3	IMP	ZFIN:ZDB-GENO-200827-2	Zfish	PMID:31476133
Molecular Function	GO:0008432	JUN kinase binding	Mapk8ip3	IPI	UniProtKB:Q61831\|UniProtKB:Q91Y86\|UniProtKB:Q9WTU6	Mouse	MGI:MGI:1890011\|PMID:10523642
Molecular Function	GO:0019894	kinesin binding	Mapk8ip3	IPI	UniProtKB:O88447	Mouse	MGI:MGI:1352260\|PMID:10629060
Molecular Function	GO:0019894	kinesin binding	Mapk8ip3	IDA		Mouse	MGI:MGI:6162406\|PMID:25944905
Molecular Function	GO:0005078	MAP-kinase scaffold activity	Mapk8ip3	IDA		Mouse	MGI:MGI:1890011\|PMID:10523642
Molecular Function	GO:0005078	MAP-kinase scaffold activity	Mapk8ip3	IPI	UniProtKB:Q91Y86	Mouse	MGI:MGI:1352260\|PMID:10629060
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	Mapk8ip3	IPI	UniProtKB:P47809	Mouse	MGI:MGI:1890011\|PMID:10523642
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	Mapk8ip3	IPI	RGD:1307040	Rat	PMID:16805806\|RGD:2293339
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	Mapk8ip3	IPI	UniProtKB:P04049\|UniProtKB:P53349	Mouse	MGI:MGI:1890011\|PMID:10523642
Molecular Function	GO:0005515	protein binding	MAPK8IP3	IPI	UniProtKB:Q5SW96	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	MAPK8IP3	IPI	UniProtKB:O75771	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAPK8IP3	IPI	UniProtKB:Q07866-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAPK8IP3	IPI	UniProtKB:Q5SW96	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAPK8IP3	IPI	UniProtKB:Q86XF7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MAPK8IP3	IPI	UniProtKB:Q9BR01	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	UniProtKB:Q5S007	Mouse	MGI:MGI:5487757\|PMID:20173330
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	UniProtKB:O88447\|UniProtKB:O88448\|UniProtKB:P28738	Mouse	MGI:MGI:5292602\|PMID:21750526
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	UniProtKB:Q03351\|UniProtKB:Q63604	Mouse	MGI:MGI:6162386\|PMID:21775604
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	UniProtKB:P04049\|UniProtKB:P31938\|UniProtKB:P47809\|UniProtKB:P53349\|UniProtKB:Q61831	Mouse	MGI:MGI:1890011\|PMID:10523642
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	UniProtKB:O88447\|UniProtKB:O88448	Mouse	MGI:MGI:2148806\|PMID:11106729
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	UniProtKB:P62331	Mouse	MGI:MGI:4457975\|PMID:20493856
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	PR:O35099	Mouse	PMID:15767678
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	PR:Q80XI6	Mouse	PMID:15767678
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	PR:Q8CE90	Mouse	PMID:15767678
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	PR:Q61831	Mouse	PMID:15767678
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	UniProtKB:P49187	Rat	PMID:21076496\|RGD:13673827
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	UniProtKB:P37285\|UniProtKB:Q63604	Rat	PMID:21775604\|RGD:13673858
Molecular Function	GO:0005515	protein binding	Mapk8ip3	IPI	UniProtKB:Q498M5	Rat	PMID:22128169\|RGD:13673844
Cellular Component	GO:0030673	axolemma	Mapk8ip3	IDA		Mouse	PMID:16606357
Cellular Component	GO:0030424	axon	Mapk8ip3	IDA		Mouse	MGI:MGI:6162406\|PMID:25944905
Cellular Component	GO:0030424	axon	Mapk8ip3	IDA		Rat	PMID:21775604\|RGD:13673858
Cellular Component	GO:0030424	axon	Mapk8ip3	IDA		Rat	PMID:23576431\|RGD:13673742
Cellular Component	GO:0030424	axon	mapk8ip3	IMP	ZFIN:ZDB-GENO-130508-5	Zfish	PMID:23468645\|ZFIN:ZDB-PUB-130402-5
Cellular Component	GO:1904115	axon cytoplasm	mapk8ip3	IMP	ZFIN:ZDB-GENO-130508-5	Zfish	PMID:23468645\|ZFIN:ZDB-PUB-130402-5
Cellular Component	GO:0044297	cell body	Mapk8ip3	IDA		Rat	PMID:23576431\|RGD:13673742
Cellular Component	GO:0005737	cytoplasm	Mapk8ip3	IDA		Mouse	MGI:MGI:1890011\|PMID:10523642
Cellular Component	GO:0005737	cytoplasm	Mapk8ip3	IDA		Mouse	PMID:15767678
Cellular Component	GO:0005737	cytoplasm	Mapk8ip3	IDA		Mouse	PMID:10629060
Cellular Component	GO:0030425	dendrite	Mapk8ip3	IDA		Mouse	PMID:16606357
Cellular Component	GO:0030425	dendrite	Mapk8ip3	IDA		Rat	PMID:21775604\|RGD:13673858
Cellular Component	GO:0000139	Golgi membrane	Mapk8ip3	IDA		Mouse	MGI:MGI:2148806\|PMID:11106729
Cellular Component	GO:0043005	neuron projection	Mapk8ip3	IDA		Rat	PMID:15033528\|RGD:1579742
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Mapk8ip3	IDA		Rat	PMID:21775604\|RGD:13673858
Cellular Component	GO:0005886	plasma membrane	Mapk8ip3	IDA		Mouse	PMID:16606357
Cellular Component	GO:0005790	smooth endoplasmic reticulum	Mapk8ip3	IDA		Mouse	PMID:16606357
Biological Process	GO:0099641	anterograde axonal protein transport	Mapk8ip3	IMP		Mouse	MGI:MGI:6102023\|PMID:28259553
Biological Process	GO:0099641	anterograde axonal protein transport	Mapk8ip3	IMP		Rat	PMID:21775604\|RGD:13673858
Biological Process	GO:0061564	axon development	Mapk8ip3	IMP		Mouse	MGI:MGI:5502974\|PMID:23576431
Biological Process	GO:0061564	axon development	Mapk8ip3	IMP		Mouse	MGI:MGI:6162406\|PMID:25944905
Biological Process	GO:0061564	axon development	Mapk8ip3	IMP		Rat	PMID:23576431\|RGD:13673742
Biological Process	GO:0061564	axon development	Mapk8ip3	IMP		Rat	PMID:25944905\|RGD:13673780
Biological Process	GO:0048675	axon extension	mapk8ip3	IMP	ZFIN:ZDB-CRISPR-200312-1,ZFIN:ZDB-CRISPR-200312-2,ZFIN:ZDB-CRISPR-200312-3	Zfish	PMID:31476133
Biological Process	GO:0048675	axon extension	mapk8ip3	IMP	ZFIN:ZDB-GENO-200827-1	Zfish	PMID:31476133
Biological Process	GO:0007411	axon guidance	Mapk8ip3	IMP	MGI:MGI:3527900	Mouse	PMID:15572149
Biological Process	GO:0031103	axon regeneration	Mapk8ip3	IMP		Rat	PMID:25944905\|RGD:13673780
Biological Process	GO:0030900	forebrain development	Mapk8ip3	IMP	MGI:MGI:3527900	Mouse	PMID:15572149
Biological Process	GO:0030900	forebrain development	Mapk8ip3	IMP	MGI:MGI:3053053	Mouse	PMID:12897243
Biological Process	GO:0001701	in utero embryonic development	Mapk8ip3	IMP	MGI:MGI:3527900	Mouse	PMID:18324732
Biological Process	GO:0007254	JNK cascade	Mapk8ip3	IDA		Mouse	PMID:10629060
Biological Process	GO:0048286	lung alveolus development	Mapk8ip3	IMP	MGI:MGI:3527900	Mouse	PMID:18324732
Biological Process	GO:0060425	lung morphogenesis	Mapk8ip3	IMP	MGI:MGI:3527900	Mouse	PMID:18324732
Biological Process	GO:0043066	negative regulation of apoptotic process	MAPK8IP3	IMP		Human	PMID:33022230
Biological Process	GO:0031175	neuron projection development	Mapk8ip3	IEP		Rat	PMID:15033528\|RGD:1579742
Biological Process	GO:0046330	positive regulation of JNK cascade	Mapk8ip3	IMP		Rat	PMID:21076496\|RGD:13673827
Biological Process	GO:0043507	positive regulation of JUN kinase activity	Mapk8ip3	IDA		Mouse	MGI:MGI:1890011\|PMID:10523642
Biological Process	GO:0043507	positive regulation of JUN kinase activity	Mapk8ip3	IDA		Mouse	PMID:15767678
Biological Process	GO:0045666	positive regulation of neuron differentiation	Mapk8ip3	IMP		Rat	PMID:17188238\|RGD:2302281
Biological Process	GO:2001224	positive regulation of neuron migration	Mapk8ip3	IMP		Mouse	MGI:MGI:6102023\|PMID:28259553
Biological Process	GO:0009791	post-embryonic development	Mapk8ip3	IMP	MGI:MGI:3527900	Mouse	PMID:18324732
Biological Process	GO:0008104	protein localization	Mapk8ip3	IMP	MGI:MGI:3527900	Mouse	PMID:15572149
Biological Process	GO:0050821	protein stabilization	MAPK8IP3	IMP		Human	PMID:33022230
Biological Process	GO:0010468	regulation of gene expression	Mapk8ip3	IDA		Mouse	PMID:18324732
Biological Process	GO:0046328	regulation of JNK cascade	Mapk8ip3	IDA		Mouse	MGI:MGI:1352260\|PMID:10629060
Biological Process	GO:0046328	regulation of JNK cascade	mapk8ip3	IMP	ZFIN:ZDB-GENO-130508-5	Zfish	PMID:23468645
Biological Process	GO:0007585	respiratory gaseous exchange by respiratory system	Mapk8ip3	IMP	MGI:MGI:3053053	Mouse	PMID:12897243
Biological Process	GO:0099642	retrograde axonal protein transport	mapk8ip3	IMP	ZFIN:ZDB-GENO-200827-2	Zfish	PMID:31476133
Biological Process	GO:0008090	retrograde axonal transport	mapk8ip3	IMP	ZFIN:ZDB-GENO-130508-5	Zfish	PMID:23468645
Biological Process	GO:0016192	vesicle-mediated transport	Mapk8ip3	IDA		Mouse	MGI:MGI:2148806\|PMID:11106729

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.