Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAPK8IP2
  • Mouse genes Mapk8ip2
  • Rat genes Mapk8ip2
  • Zfish genes mapk8ip2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mapk8ip2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019894	kinesin binding	Mapk8ip2	IPI	UniProtKB:O88447	Mouse	MGI:MGI:3688042|PMID:11238452
Molecular Function	GO:0005078	MAP-kinase scaffold activity	MAPK8IP2	IDA		Human	PMID:10756100
Molecular Function	GO:0005515	protein binding	MAPK8IP2	IPI	UniProtKB:P00533	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	MAPK8IP2	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	MAPK8IP2	IPI	UniProtKB:Q5S007	Human	PMID:20173330
Molecular Function	GO:0005515	protein binding	MAPK8IP2	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	MAPK8IP2	IPI	UniProtKB:O15205	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	MAPK8IP2	IPI	UniProtKB:Q15389-2	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	MAPK8IP2	IPI	UniProtKB:Q53HF2	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	MAPK8IP2	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Mapk8ip2	IPI	UniProtKB:A2ARV4|UniProtKB:Q91ZX7	Mouse	MGI:MGI:3687813|PMID:10827173
Molecular Function	GO:0005515	protein binding	Mapk8ip2	IPI	UniProtKB:P14599	Mouse	MGI:MGI:3687934|PMID:11912189
Molecular Function	GO:0005515	protein binding	Mapk8ip2	IPI	UniProtKB:Q498M5	Rat	PMID:22128169|RGD:13673844
Molecular Function	GO:0019901	protein kinase binding	MAPK8IP2	IPI	UniProtKB:P45983	Human	PMID:10490659
Molecular Function	GO:0044877	protein-containing complex binding	Mapk8ip2	IDA		Rat	PMID:12024021|RGD:2302280
Cellular Component	GO:0005737	cytoplasm	MAPK8IP2	IDA		Human	PMID:10490659
Cellular Component	GO:0005737	cytoplasm	Mapk8ip2	IDA		Mouse	PMID:16018997
Cellular Component	GO:0043025	neuronal cell body	Mapk8ip2	IDA		Mouse	PMID:16301330
Cellular Component	GO:0014069	postsynaptic density	Mapk8ip2	IDA		Mouse	MGI:MGI:4849330|PMID:21048139
Cellular Component	GO:0032991	protein-containing complex	Mapk8ip2	IDA		Rat	PMID:12024021|RGD:2302280
Biological Process	GO:0001662	behavioral fear response	Mapk8ip2	IMP		Mouse	MGI:MGI:4849330|PMID:21048139
Biological Process	GO:0048813	dendrite morphogenesis	Mapk8ip2	IMP		Mouse	MGI:MGI:4849330|PMID:21048139
Biological Process	GO:0060079	excitatory postsynaptic potential	Mapk8ip2	IMP		Mouse	MGI:MGI:4849330|PMID:21048139
Biological Process	GO:0007254	JNK cascade	Mapk8ip2	IDA		Mouse	PMID:10827199
Biological Process	GO:0007617	mating behavior	Mapk8ip2	IMP		Mouse	MGI:MGI:4849330|PMID:21048139
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	MAPK8IP2	IDA		Human	PMID:10756100
Biological Process	GO:0046958	nonassociative learning	Mapk8ip2	IMP		Mouse	MGI:MGI:4849330|PMID:21048139
Biological Process	GO:0032874	positive regulation of stress-activated MAPK cascade	Mapk8ip2	IMP		Rat	PMID:12024021|RGD:2302280
Biological Process	GO:2000311	regulation of AMPA receptor activity	Mapk8ip2	IMP		Mouse	MGI:MGI:4849330|PMID:21048139
Biological Process	GO:0046328	regulation of JNK cascade	MAPK8IP2	IDA		Human	PMID:10490659
Biological Process	GO:2000310	regulation of NMDA receptor activity	Mapk8ip2	IMP		Mouse	MGI:MGI:4849330|PMID:21048139
Biological Process	GO:0010469	regulation of signaling receptor activity	Mapk8ip2	IMP		Mouse	MGI:MGI:4849330|PMID:21048139
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	Mapk8ip2	IMP		Mouse	MGI:MGI:4849330|PMID:21048139
Biological Process	GO:0035176	social behavior	Mapk8ip2	IMP		Mouse	MGI:MGI:4849330|PMID:21048139

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern