Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Mapk8ip1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes MAPK8IP1
- Mouse genes Mapk8ip1
- Rat genes Mapk8ip1
- Zfish genes mapk8ip1a,mapk8ip1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mapk8ip1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Mapk8ip1	IPI	UniProtKB:Q9R237-3	Rat	PMID:16456539\|RGD:8554208
Molecular Function	GO:0008432	JUN kinase binding	Mapk8ip1	IPI	RGD:621506	Rat	PMID:17348686\|RGD:2298766
Molecular Function	GO:0008432	JUN kinase binding	Mapk8ip1	IPI	RGD:628847	Rat	PMID:17348686\|RGD:2298766
Molecular Function	GO:0019894	kinesin binding	MAPK8IP1	IPI	UniProtKB:Q07866	Human	PMID:11238452
Molecular Function	GO:0019894	kinesin binding	Mapk8ip1	IPI	UniProtKB:O88446	Mouse	MGI:MGI:3688042\|PMID:11238452
Molecular Function	GO:0005078	MAP-kinase scaffold activity	MAPK8IP1	IPI	UniProtKB:P45983	Human	PMID:11238452
Molecular Function	GO:0005078	MAP-kinase scaffold activity	Mapk8ip1	IMP		Rat	PMID:17348686\|RGD:2298766
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	Mapk8ip1	IPI	RGD:1560043	Rat	PMID:15816852\|RGD:1579811
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	Mapk8ip1	IPI	RGD:1560043	Rat	PMID:17348686\|RGD:2298766
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	Mapk8ip1	IPI	RGD:1359261	Rat	PMID:17348686\|RGD:2298766
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:P12023	Human	PMID:11517249
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:O43283	Human	PMID:11726277
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:P00533	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:O14733	Human	PMID:16840345
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:O43318	Human	PMID:16840345
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:P45983	Human	PMID:16840345
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:O43318	Human	PMID:17709393
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:O14733	Human	PMID:18286207
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:O43318	Human	PMID:18286207
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:P45983	Human	PMID:18286207
Molecular Function	GO:0005515	protein binding	MAPK8IP1	IPI	UniProtKB:P04626	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Mapk8ip1	IPI	UniProtKB:Q5S007	Mouse	MGI:MGI:5487757\|PMID:20173330
Molecular Function	GO:0005515	protein binding	Mapk8ip1	IPI	UniProtKB:Q86Y07-2	Mouse	MGI:MGI:3836104\|PMID:18286207
Molecular Function	GO:0005515	protein binding	Mapk8ip1	IPI	UniProtKB:A2ARV4\|UniProtKB:Q91ZX7	Mouse	MGI:MGI:3687813\|PMID:10827173
Molecular Function	GO:0005515	protein binding	Mapk8ip1	IPI	UniProtKB:Q9JI18	Mouse	MGI:MGI:3821918\|PMID:19071120
Molecular Function	GO:0005515	protein binding	Mapk8ip1	IPI	UniProtKB:Q62073	Mouse	MGI:MGI:3843421\|PMID:17709393
Molecular Function	GO:0005515	protein binding	Mapk8ip1	IPI	UniProtKB:Q69ZI1	Mouse	MGI:MGI:5546548\|PMID:23963642
Molecular Function	GO:0005515	protein binding	Mapk8ip1	IPI	UniProtKB:P12023-2\|UniProtKB:P12023\|UniProtKB:P45983	Mouse	MGI:MGI:3688062\|PMID:11517249
Molecular Function	GO:0005515	protein binding	Mapk8ip1	IPI	RGD:2081	Rat	PMID:12194869\|RGD:632178
Molecular Function	GO:0005515	protein binding	Mapk8ip1	IPI	UniProtKB:P49187	Rat	PMID:21076496\|RGD:13673827
Molecular Function	GO:0005515	protein binding	Mapk8ip1	IPI	UniProtKB:Q498M5	Rat	PMID:22128169\|RGD:13673844
Molecular Function	GO:0019901	protein kinase binding	Mapk8ip1	IPI	UniProtKB:Q91Y86	Mouse	MGI:MGI:2182167\|PMID:11562351
Cellular Component	GO:0030424	axon	Mapk8ip1	IDA		Mouse	PMID:10712642
Cellular Component	GO:0044295	axonal growth cone	Mapk8ip1	IDA		Rat	PMID:10712642\|RGD:8553882
Cellular Component	GO:0005737	cytoplasm	MAPK8IP1	IDA		Human	PMID:10574993
Cellular Component	GO:0005737	cytoplasm	Mapk8ip1	IDA		Mouse	MGI:MGI:3690211\|PMID:10712642
Cellular Component	GO:0005737	cytoplasm	Mapk8ip1	IDA		Rat	PMID:10773432\|RGD:1582317
Cellular Component	GO:0005737	cytoplasm	Mapk8ip1	IDA		Rat	PMID:9442013\|RGD:633194
Cellular Component	GO:0005829	cytosol	Mapk8ip1	IDA		Mouse	PMID:10712642
Cellular Component	GO:0005829	cytosol	Mapk8ip1	IDA		Rat	PMID:15816852\|RGD:1579811
Cellular Component	GO:0030425	dendrite	Mapk8ip1	IDA		Mouse	PMID:10712642
Cellular Component	GO:0044294	dendritic growth cone	Mapk8ip1	IDA		Rat	PMID:10712642\|RGD:8553882
Cellular Component	GO:0044302	dentate gyrus mossy fiber	Mapk8ip1	IDA		Mouse	PMID:10712642
Cellular Component	GO:0016020	membrane	Mapk8ip1	IDA		Mouse	PMID:10712642
Cellular Component	GO:0043005	neuron projection	Mapk8ip1	IDA		Mouse	PMID:16301330
Cellular Component	GO:0043025	neuronal cell body	Mapk8ip1	IDA		Mouse	PMID:10712642
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Mapk8ip1	IDA		Rat	PMID:15816852\|RGD:1579811
Cellular Component	GO:0005886	plasma membrane	MAPK8IP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045202	synapse	Mapk8ip1	IDA		Mouse	PMID:10712642
Biological Process	GO:0007258	JUN phosphorylation	Mapk8ip1	IDA		Mouse	PMID:9235893
Biological Process	GO:0043066	negative regulation of apoptotic process	Mapk8ip1	IDA		Rat	PMID:10098834\|RGD:70789
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	Mapk8ip1	IDA		Mouse	PMID:10098834
Biological Process	GO:0046329	negative regulation of JNK cascade	Mapk8ip1	IMP		Rat	PMID:12064607\|RGD:1299562
Biological Process	GO:0043508	negative regulation of JUN kinase activity	Mapk8ip1	IMP		Rat	PMID:12064607\|RGD:1299562
Biological Process	GO:0043508	negative regulation of JUN kinase activity	Mapk8ip1	IMP		Rat	PMID:21076496\|RGD:13673827
Biological Process	GO:0046330	positive regulation of JNK cascade	Mapk8ip1	IMP		Mouse	MGI:MGI:5546548\|PMID:23963642
Biological Process	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation	Mapk8ip1	IMP		Mouse	MGI:MGI:5546548\|PMID:23963642
Biological Process	GO:0006355	regulation of DNA-templated transcription	Mapk8ip1	IDA		Mouse	PMID:9235893
Biological Process	GO:0046328	regulation of JNK cascade	Mapk8ip1	IMP		Mouse	MGI:MGI:2182167\|PMID:11562351
Biological Process	GO:0007165	signal transduction	Mapk8ip1	IDA		Mouse	PMID:9235893
Biological Process	GO:0007165	signal transduction	Mapk8ip1	IDA		Rat	PMID:10098834\|RGD:70789
Biological Process	GO:0016192	vesicle-mediated transport	Mapk8ip1	IDA		Mouse	PMID:16301330

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.