Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LOXL3
  • Mouse genes Loxl3
  • Rat genes Loxl3
  • Zfish genes loxl3a,loxl3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Loxl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001968	fibronectin binding	Loxl3	IDA		Mouse	MGI:MGI:5825413|PMID:26954549
Molecular Function	GO:0005515	protein binding	LOXL3	IPI	UniProtKB:O95863	Human	PMID:16096638
Molecular Function	GO:0005515	protein binding	LOXL3	IPI	UniProtKB:P40763	Human	PMID:28065600
Molecular Function	GO:0005515	protein binding	LOXL3	IPI	UniProtKB:Q7TSK7	Human	PMID:29758265
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	LOXL3	IDA		Human	PMID:28065600
Molecular Function	GO:0004720	protein-lysine 6-oxidase activity	Loxl3	IDA		Mouse	MGI:MGI:5825413|PMID:26954549
Cellular Component	GO:0005737	cytoplasm	LOXL3	IDA		Human	PMID:28065600
Cellular Component	GO:0005576	extracellular region	LOXL3	IDA		Human	PMID:11284725
Cellular Component	GO:0005615	extracellular space	Loxl3	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Loxl3	IDA		Mouse	MGI:MGI:5825413|PMID:26954549
Cellular Component	GO:0005634	nucleus	LOXL3	IDA		Human	PMID:28065600
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	loxl3b	IMP	ZFIN:ZDB-MRPHLNO-110802-3	Zfish	PMID:21244857
Biological Process	GO:0001837	epithelial to mesenchymal transition	LOXL3	IDA		Human	PMID:16096638
Biological Process	GO:1905590	fibronectin fibril organization	Loxl3	IMP		Mouse	MGI:MGI:5825413|PMID:26954549
Biological Process	GO:0006954	inflammatory response	Loxl3	IMP		Mouse	MGI:MGI:5825383|PMID:28065600
Biological Process	GO:0030324	lung development	Loxl3	IMP		Mouse	MGI:MGI:5825408|PMID:27645581
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	LOXL3	IDA		Human	PMID:16096638
Biological Process	GO:2000329	negative regulation of T-helper 17 cell lineage commitment	Loxl3	IMP		Mouse	MGI:MGI:5825383|PMID:28065600
Biological Process	GO:0018057	peptidyl-lysine oxidation	LOXL3	IDA		Human	PMID:28065600
Biological Process	GO:0018057	peptidyl-lysine oxidation	Loxl3	IDA		Mouse	MGI:MGI:5825413|PMID:26954549
Biological Process	GO:2001046	positive regulation of integrin-mediated signaling pathway	Loxl3	IMP		Mouse	MGI:MGI:5825413|PMID:26954549
Biological Process	GO:0060021	roof of mouth development	Loxl3	IMP		Mouse	MGI:MGI:5697239|PMID:26307084
Biological Process	GO:0061053	somite development	Loxl3	IMP		Mouse	MGI:MGI:5825413|PMID:26954549
Biological Process	GO:0021510	spinal cord development	Loxl3	IMP		Mouse	MGI:MGI:5697239|PMID:26307084

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern