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Loxl3
Gene Detail
 Symbol
Name
ID
Loxl3
lysyl oxidase-like 3
MGI:1337004
Synonyms Lor2
Feature Type protein coding gene
Genetic Map
Chromosome 6
35.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:83034173-83052562 bp, + strand
From VEGA annotation of GRCm38

  18390 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56591  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Loxl3

Human
homologs
Human Homolog LOXL3, lysyl oxidase-like 3
NCBI Gene ID 84695
neXtProt AC  NX_P58215
Human Synonyms  LOXL
Human Chr (Location)  2p13; chr2:74532258-74553964 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Loxl3 interacts with 271 markers (Mir1b, Mir10b, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process epithelial to mesenchymal transition, negative regulation of transcription, DNA-templated, ...
Component extracellular region, membrane
Function aspartate oxidase activity, copper ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (171)    Tissues (30)    Images (22)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 171
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) Genomic(3) cDNA(7) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000022487 (Evidence)
Ensembl Gene ModelENSMUSG00000000693 (Evidence)
Entrez Gene16950 (Evidence)
NIA Mouse Gene IndexU007069
EC1.4.3.-
Consensus CDS ProjectCCDS20266.1
International Mouse Knockout Project StatusLoxl3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022487 VEGA Gene Model | MGI Sequence Detail 18390 C57BL/6J ±  kb
transcript OTTMUST00000053823 VEGA | MGI Sequence Detail 4098 Not Applicable 
polypeptide OTTMUSP00000025614 VEGA | MGI Sequence Detail 754 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(147 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001695 Lysyl oxidase
InterPro IPR019828 Lysyl oxidase, conserved site
InterPro IPR001190 Speract/scavenger receptor
InterPro IPR017448 Speract/scavenger receptor-related
Protein Ontology PR:000009886 lysyl oxidase homolog 3
References (Earliest) J:52798 Jang W, et al., Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Res. 1999 Jan;9(1):53-61
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory