Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KIF7
  • Mouse genes Kif7
  • Rat genes Kif7
  • Zfish genes kif7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kif7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Kif7	IPI	UniProtKB:B7ZNG0-2	Mouse	MGI:MGI:5620586|PMID:24952464
Molecular Function	GO:0003777	microtubule motor activity	KIF7	IDA		Human	PMID:21633164
Molecular Function	GO:0005515	protein binding	KIF7	IPI	UniProtKB:P10071	Human	PMID:19592253
Molecular Function	GO:0005515	protein binding	KIF7	IPI	UniProtKB:P47806	Human	PMID:19592253
Molecular Function	GO:0005515	protein binding	KIF7	IPI	UniProtKB:Q99835	Human	PMID:19592253
Molecular Function	GO:0005515	protein binding	KIF7	IPI	UniProtKB:Q9Z0P7	Human	PMID:19592253
Molecular Function	GO:0005515	protein binding	KIF7	IPI	UniProtKB:O15259	Human	PMID:21633164
Molecular Function	GO:0005515	protein binding	Kif7	IPI	UniProtKB:E9Q9R9|UniProtKB:P56726	Mouse	MGI:MGI:5617062|PMID:25644602
Molecular Function	GO:0005515	protein binding	Kif7	IPI	UniProtKB:Q61602	Mouse	MGI:MGI:4357736|PMID:19549984
Molecular Function	GO:0005515	protein binding	Kif7	IPI	UniProtKB:Q61602	Mouse	PMID:27046536
Molecular Function	GO:0005515	protein binding	kif7	IPI	UniProtKB:Q800Z9	Zfish	PMID:15647323
Cellular Component	GO:0036064	ciliary basal body	Kif7	IDA		Mouse	MGI:MGI:5617062|PMID:25644602
Cellular Component	GO:0097542	ciliary tip	Kif7	IDA		Mouse	PMID:29038301
Cellular Component	GO:0005929	cilium	KIF7	IDA		Human	PMID:19592253
Cellular Component	GO:0005929	cilium	Kif7	IDA		Mouse	MGI:MGI:4355635|PMID:19666503
Cellular Component	GO:0005929	cilium	kif7	IDA		Zfish	PMID:24339784
Cellular Component	GO:0005737	cytoplasm	kif7	IDA		Zfish	PMID:15647323
Cellular Component	GO:0005737	cytoplasm	kif7	IDA		Zfish	PMID:24339784
Cellular Component	GO:0035301	Hedgehog signaling complex	kif7	IDA		Zfish	PMID:15647323
Biological Process	GO:0035904	aorta development	Kif7	IMP		Mouse	PMID:25807483
Biological Process	GO:0003279	cardiac septum development	Kif7	IMP		Mouse	PMID:25807483
Biological Process	GO:0060976	coronary vasculature development	Kif7	IMP		Mouse	PMID:25807483
Biological Process	GO:0007368	determination of left/right symmetry	kif7	IMP	ZFIN:ZDB-CRISPR-210719-3	Zfish	PMID:32738303
Biological Process	GO:0007368	determination of left/right symmetry	kif7	IMP	ZFIN:ZDB-MRPHLNO-050307-1	Zfish	PMID:19305393
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	Kif7	IMP		Mouse	MGI:MGI:4357736|PMID:19549984
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	Kif7	IMP		Mouse	MGI:MGI:4359116|PMID:19592253
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	Kif7	IMP		Mouse	MGI:MGI:4355635|PMID:19666503
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	kif7	IMP	ZFIN:ZDB-GENO-150828-17	Zfish	PMID:24339784
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	kif7	IMP	ZFIN:ZDB-MRPHLNO-050307-1	Zfish	PMID:15647323
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	kif7	IMP	ZFIN:ZDB-MRPHLNO-050307-2	Zfish	PMID:15647323
Biological Process	GO:0035845	photoreceptor cell outer segment organization	kif7	IMP	ZFIN:ZDB-GENO-170811-4	Zfish	PMID:28341548
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Kif7	IMP		Mouse	MGI:MGI:4357736|PMID:19549984
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Kif7	IMP		Mouse	MGI:MGI:4355635|PMID:19666503

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern