Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNQ3
  • Mouse genes Kcnq3
  • Rat genes Kcnq3
  • Zfish genes kcnq3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnq3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005516	calmodulin binding	KCNQ3	IDA		Human	PMID:27564677
Molecular Function	GO:0005516	calmodulin binding	Kcnq3	IPI	PR:Q8K3F6	Mouse	PMID:12223552
Molecular Function	GO:0005516	calmodulin binding	Kcnq3	IDA		Rat	PMID:24333508|RGD:9686369
Molecular Function	GO:0005267	potassium channel activity	Kcnq3	IMP	MGI:MGI:3830636	Mouse	PMID:19060215
Molecular Function	GO:0005515	protein binding	KCNQ3	IPI	UniProtKB:P0DP23	Human	PMID:27564677
Molecular Function	GO:0019901	protein kinase binding	Kcnq3	IPI	RGD:620795	Rat	PMID:15304482|RGD:9686368
Molecular Function	GO:0044325	transmembrane transporter binding	Kcnq3	IPI	RGD:736658	Rat	PMID:24333508|RGD:9686369
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Kcnq3	IPI	RGD:1344203	Rat	PMID:17322297|RGD:9686388
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	Kcnq3	IGI	MGI:MGI:1309503	Mouse	PMID:12223552
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNQ3	IDA		Human	PMID:11159685
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNQ3	IDA		Human	PMID:27564677
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnq3	IDA		Rat	PMID:9836639|RGD:68807
Cellular Component	GO:0043194	axon initial segment	Kcnq3	IDA		Mouse	MGI:MGI:3617955|PMID:16525039
Cellular Component	GO:0043194	axon initial segment	Kcnq3	IDA		Rat	PMID:24333508|RGD:9686369
Cellular Component	GO:0009986	cell surface	Kcnq3	IDA		Mouse	PMID:12223552
Cellular Component	GO:0009986	cell surface	Kcnq3	IDA		Rat	PMID:15304482|RGD:9686368
Cellular Component	GO:0030425	dendrite	Kcnq3	IDA		Rat	PMID:24333508|RGD:9686369
Cellular Component	GO:0045121	membrane raft	Kcnq3	IDA		Rat	PMID:19726551|RGD:9686435
Cellular Component	GO:0043005	neuron projection	Kcnq3	IDA		Rat	PMID:12832524|RGD:9686367
Cellular Component	GO:0043025	neuronal cell body	Kcnq3	IDA		Rat	PMID:12832524|RGD:9686367
Cellular Component	GO:0033268	node of Ranvier	Kcnq3	IDA		Mouse	MGI:MGI:3617955|PMID:16525039
Cellular Component	GO:0005886	plasma membrane	KCNQ3	IDA		Human	PMID:10788442
Cellular Component	GO:0005886	plasma membrane	KCNQ3	IDA		Human	PMID:11159685
Cellular Component	GO:0005886	plasma membrane	Kcnq3	IDA		Mouse	MGI:MGI:3617955|PMID:16525039
Cellular Component	GO:0005886	plasma membrane	Kcnq3	IDA		Rat	PMID:9836639|RGD:68807
Cellular Component	GO:0036477	somatodendritic compartment	Kcnq3	IDA		Rat	PMID:24333508|RGD:9686369
Cellular Component	GO:0045202	synapse	kcnq3	IMP	ZFIN:ZDB-MRPHLNO-120124-1	Zfish	PMID:21692188|ZFIN:ZDB-PUB-110629-20
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNQ3	IDA		Human	PMID:11159685
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNQ3	IDA		Human	PMID:27564677
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnq3	IGI	MGI:MGI:1309503	Mouse	PMID:12223552
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnq3	IDA		Rat	PMID:9836639|RGD:68807
Biological Process	GO:0071242	cellular response to ammonium ion	Kcnq3	IMP		Rat	PMID:24333508|RGD:9686369
Biological Process	GO:0007268	chemical synaptic transmission	kcnq3	IMP	ZFIN:ZDB-MRPHLNO-120124-1	Zfish	PMID:21692188
Biological Process	GO:0007268	chemical synaptic transmission	kcnq3	IMP	ZFIN:ZDB-MRPHLNO-120124-2	Zfish	PMID:21692188
Biological Process	GO:0051649	establishment of localization in cell	Kcnq3	IMP	MGI:MGI:3830636	Mouse	PMID:19060215
Biological Process	GO:0061548	ganglion development	Kcnq3	IEP		Rat	PMID:12832524|RGD:9686367
Biological Process	GO:0060081	membrane hyperpolarization	Kcnq3	IMP	MGI:MGI:3830636	Mouse	PMID:19060215
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Kcnq3	IMP		Rat	PMID:15304482|RGD:9686368
Biological Process	GO:0014003	oligodendrocyte development	Kcnq3	IEP		Rat	PMID:21750731|RGD:9686431
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNQ3	IDA		Human	PMID:11159685
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNQ3	IDA		Human	PMID:27564677
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnq3	IMP	MGI:MGI:3830636	Mouse	PMID:19060215
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnq3	IDA		Rat	PMID:9836639|RGD:68807

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern