Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kcnn2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KCNN2
- Mouse genes Kcnn2
- Rat genes Kcnn2
- Zfish genes kcnn2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051393	alpha-actinin binding	KCNN2	IPI	UniProtKB:P35609	Human	PMID:17110593
Molecular Function	GO:0015269	calcium-activated potassium channel activity	KCNN2	IDA		Human	PMID:17110593
Molecular Function	GO:0005516	calmodulin binding	Kcnn2	IMP		Rat	PMID:18701069\|RGD:7205441
Molecular Function	GO:0005242	inward rectifier potassium channel activity	KCNN2	IDA		Human	PMID:12382077
Molecular Function	GO:0005515	protein binding	KCNN2	IPI	UniProtKB:P35609	Human	PMID:19815520
Molecular Function	GO:0005515	protein binding	KCNN2	IPI	UniProtKB:P21333	Human	PMID:24951510
Molecular Function	GO:0005515	protein binding	Kcnn2	IPI	UniProtKB:Q9WV34	Mouse	MGI:MGI:5766670\|PMID:26880549
Molecular Function	GO:0019904	protein domain specific binding	KCNN2	IPI	UniProtKB:P35609	Human	PMID:19815520
Molecular Function	GO:0042803	protein homodimerization activity	KCNN2	IPI	UniProtKB:Q9H2S1	Human	PMID:17110593
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	KCNN2	IDA		Human	PMID:12382077
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	KCNN2	IMP		Human	PMID:19815520
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	KCNN2	IDA		Human	PMID:24951510
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	Kcnn2	IMP		Mouse	MGI:MGI:4366185\|PMID:19815520
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	Kcnn2	IMP		Mouse	MGI:MGI:5292192\|PMID:19139040
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	Kcnn2	IDA		Rat	PMID:11323678\|RGD:8554362
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	Kcnn2	IMP		Rat	PMID:14559917\|RGD:1358336
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	Kcnn2	IDA		Rat	PMID:18701069\|RGD:7205441
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	Kcnn2	IMP		Rat	PMID:19969350\|RGD:8693687
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	Kcnn2	IMP		Rat	PMID:21521760\|RGD:7205439
Cellular Component	GO:0009986	cell surface	KCNN2	IDA		Human	PMID:19815520
Cellular Component	GO:0043197	dendritic spine	Kcnn2	IDA		Mouse	PMID:17347645
Cellular Component	GO:0043197	dendritic spine	Kcnn2	IDA		Rat	PMID:21521760\|RGD:7205439
Cellular Component	GO:0098978	glutamatergic synapse	Kcnn2	IDA		Mouse	PMID:25565979
Cellular Component	GO:0098978	glutamatergic synapse	Kcnn2	IDA		Mouse	PMID:26166566
Cellular Component	GO:0098978	glutamatergic synapse	Kcnn2	EXP		Mouse	PMID:26166566
Cellular Component	GO:0016020	membrane	Kcnn2	IDA		Rat	PMID:11323678\|RGD:8554362
Cellular Component	GO:0043025	neuronal cell body	Kcnn2	IDA		Rat	PMID:15680700\|RGD:7205443
Cellular Component	GO:0005886	plasma membrane	KCNN2	IDA		Human	PMID:19815520
Cellular Component	GO:0005886	plasma membrane	KCNN2	IDA		Human	PMID:27165696
Cellular Component	GO:0005886	plasma membrane	Kcnn2	IDA		Mouse	PMID:17347645
Cellular Component	GO:0045211	postsynaptic membrane	Kcnn2	IDA		Mouse	PMID:25565979
Cellular Component	GO:0042383	sarcolemma	Kcnn2	IDA		Mouse	MGI:MGI:4366185\|PMID:19815520
Cellular Component	GO:0005790	smooth endoplasmic reticulum	Kcnn2	IDA		Mouse	PMID:17347645
Cellular Component	GO:0030315	T-tubule	Kcnn2	IDA		Mouse	MGI:MGI:3771286\|PMID:17110593
Cellular Component	GO:0030018	Z disc	Kcnn2	IDA		Mouse	MGI:MGI:4366185\|PMID:19815520
Cellular Component	GO:0030018	Z disc	Kcnn2	IDA		Mouse	MGI:MGI:3771286\|PMID:17110593
Cellular Component	GO:0030018	Z disc	Kcnn2	IDA		Mouse	MGI:MGI:5578267\|PMID:24951510
Biological Process	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential	Kcnn2	IMP		Mouse	MGI:MGI:5292192\|PMID:19139040
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Kcnn2	IDA		Mouse	PMID:26166566
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Kcnn2	EXP		Mouse	PMID:26166566
Biological Process	GO:0043268	positive regulation of potassium ion transport	Kcnn2	IMP		Rat	PMID:28917524\|RGD:38508907
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNN2	IDA		Human	PMID:12382077
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNN2	IDA		Human	PMID:17110593
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNN2	IDA		Human	PMID:24951510
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnn2	IMP		Mouse	MGI:MGI:5292192\|PMID:19139040
Biological Process	GO:0006813	potassium ion transport	Kcnn2	IDA		Rat	PMID:11323678\|RGD:8554362
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	Kcnn2	IMP		Rat	PMID:21521760\|RGD:7205439
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	KCNN2	IDA		Human	PMID:17110593

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.