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Gene Ontology Browser
Term Detail
GO term:alpha-actinin binding
Synonym: alpha-actinin 1 binding
Synonym: alpha-actinin 4 binding
Synonym: nonmuscle alpha-actinin binding
GO id:GO:0051393
Definition:Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-abinding
                        is-aprotein binding
                                is-acytoskeletal protein binding
                                        is-aactinin binding
                                                is-aalpha-actinin binding [GO:0051393] (21 genes, 25 annotations)
                                                        is-amuscle alpha-actinin binding


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory