Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KALRN
  • Mouse genes Kalrn
  • Rat genes Kalrn
  • Zfish genes kalrna,kalrnb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kalrn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Kalrn	IPI	RGD:3252	Rat	PMID:8910496|RGD:728662
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	KALRN	EXP		Human	PMID:12546821
Molecular Function	GO:0005515	protein binding	Kalrn	IPI	RGD:632281	Rat	PMID:11182094|RGD:9999382
Molecular Function	GO:0005515	protein binding	Kalrn	IPI	RGD:631359	Rat	PMID:20139976|RGD:5509795
Molecular Function	GO:0005515	protein binding	Kalrn	IPI	UniProtKB:Q99K10	Rat	PMID:26078884|RGD:13210534
Molecular Function	GO:0005515	protein binding	Kalrn	IPI	UniProtKB:Q62765	Rat	PMID:31801062|RGD:150521626
Molecular Function	GO:0005515	protein binding	Kalrn	IPI	UniProtKB:Q99K10	Rat	PMID:31801062|RGD:150521626
Molecular Function	GO:0005515	protein binding	Kalrn	IPI	RGD:68327	Rat	PMID:9285789|RGD:728800
Molecular Function	GO:0005515	protein binding	Kalrn	IPI	UniProtKB:P54256	Rat	PMID:9285789|RGD:728800
Cellular Component	GO:0005829	cytosol	KALRN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	KALRN	HDA		Human	PMID:19056867
Cellular Component	GO:0098978	glutamatergic synapse	Kalrn	IDA		Rat	PMID:18031682|RGD:12050112
Cellular Component	GO:0098978	glutamatergic synapse	Kalrn	IMP		Rat	PMID:18031682|RGD:12050112
Cellular Component	GO:0043005	neuron projection	Kalrn	IDA		Rat	PMID:10777487|RGD:727293
Cellular Component	GO:0043025	neuronal cell body	Kalrn	IDA		Rat	PMID:10777487|RGD:727293
Cellular Component	GO:0005654	nucleoplasm	KALRN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Kalrn	IDA		Rat	PMID:10777487|RGD:727293
Cellular Component	GO:0014069	postsynaptic density	Kalrn	IDA		Rat	PMID:18031682|RGD:12050112
Cellular Component	GO:0014069	postsynaptic density	Kalrn	IMP		Rat	PMID:18031682|RGD:12050112
Cellular Component	GO:0098793	presynapse	Kalrn	EXP		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0098793	presynapse	Kalrn	IDA		Rat	PMID:23622064|RGD:13702180
Biological Process	GO:0008344	adult locomotory behavior	Kalrn	IMP	MGI:MGI:5551305	Mouse	PMID:23116210
Biological Process	GO:0007409	axonogenesis	Kalrn	IDA		Rat	PMID:12177196|RGD:628431
Biological Process	GO:0046959	habituation	Kalrn	IMP	MGI:MGI:5551305	Mouse	PMID:23116210
Biological Process	GO:0030097	hemopoiesis	kalrnb	IMP	ZFIN:ZDB-MRPHLNO-141013-21	Zfish	PMID:25010335
Biological Process	GO:0030097	hemopoiesis	kalrna	IMP	ZFIN:ZDB-MRPHLNO-141013-19	Zfish	PMID:25010335
Biological Process	GO:0035556	intracellular signal transduction	Kalrn	IDA		Rat	PMID:12177196|RGD:628431
Biological Process	GO:0007595	lactation	Kalrn	IMP	MGI:MGI:5551305	Mouse	PMID:23116210
Biological Process	GO:0042711	maternal behavior	Kalrn	IMP	MGI:MGI:5551305	Mouse	PMID:23116210
Biological Process	GO:0060137	maternal process involved in parturition	Kalrn	IMP	MGI:MGI:5551305	Mouse	PMID:23116210
Biological Process	GO:0007613	memory	Kalrn	IMP	MGI:MGI:4358076	Mouse	PMID:19625617
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	Kalrn	IMP		Rat	PMID:18031682|RGD:12050112
Biological Process	GO:0060125	negative regulation of growth hormone secretion	Kalrn	IMP	MGI:MGI:5551305	Mouse	PMID:23116210
Biological Process	GO:0007399	nervous system development	Kalrn	IDA		Rat	PMID:12177196|RGD:628431
Biological Process	GO:0007528	neuromuscular junction development	Kalrn	IMP	MGI:MGI:5551305	Mouse	PMID:23116210
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Kalrn	IMP		Rat	PMID:18031682|RGD:12050112
Biological Process	GO:0098989	NMDA selective glutamate receptor signaling pathway	Kalrn	IMP		Rat	PMID:18031682|RGD:12050112
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	Kalrn	IMP	MGI:MGI:4358076	Mouse	PMID:19625617
Biological Process	GO:0043547	positive regulation of GTPase activity	Kalrn	IMP	MGI:MGI:4358076	Mouse	PMID:19625617
Biological Process	GO:0050773	regulation of dendrite development	Kalrn	IDA		Rat	PMID:14627644|RGD:1358370
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	Kalrn	IDA		Rat	PMID:18031682|RGD:12050112
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	Kalrn	IMP		Rat	PMID:18031682|RGD:12050112
Biological Process	GO:0098696	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	Kalrn	IDA		Rat	PMID:18031682|RGD:12050112
Biological Process	GO:0098696	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	Kalrn	IMP		Rat	PMID:18031682|RGD:12050112
Biological Process	GO:0035176	social behavior	Kalrn	IMP	MGI:MGI:4358076	Mouse	PMID:19625617

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern