Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes JCHAIN
  • Mouse genes Jchain
  • Rat genes Jchain
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Jchain

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019862	IgA binding	JCHAIN	IMP		Human	PMID:17237408
Molecular Function	GO:0019862	IgA binding	Jchain	IDA		Mouse	MGI:MGI:5553246|PMID:17237408
Molecular Function	GO:0034987	immunoglobulin receptor binding	JCHAIN	IMP		Human	PMID:17237408
Molecular Function	GO:0034987	immunoglobulin receptor binding	JCHAIN	IDA		Human	PMID:23250751
Molecular Function	GO:0034987	immunoglobulin receptor binding	Jchain	IMP		Mouse	MGI:MGI:5553246|PMID:17237408
Molecular Function	GO:0042834	peptidoglycan binding	JCHAIN	IDA		Human	PMID:21786026
Molecular Function	GO:0031210	phosphatidylcholine binding	JCHAIN	IDA		Human	PMID:21786026
Molecular Function	GO:0042803	protein homodimerization activity	JCHAIN	IDA		Human	PMID:21786026
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	Jchain	IDA		Mouse	MGI:MGI:5553246|PMID:17237408
Molecular Function	GO:0003697	single-stranded DNA binding	JCHAIN	IDA		Human	PMID:21786026
Cellular Component	GO:0072562	blood microparticle	JCHAIN	HDA		Human	PMID:22516433
Cellular Component	GO:0071750	dimeric IgA immunoglobulin complex	JCHAIN	IMP		Human	PMID:17237408
Cellular Component	GO:0071750	dimeric IgA immunoglobulin complex	Jchain	IMP		Mouse	MGI:MGI:5553246|PMID:17237408
Cellular Component	GO:0070062	extracellular exosome	JCHAIN	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	JCHAIN	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	JCHAIN	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	JCHAIN	HDA		Human	PMID:22664934
Cellular Component	GO:0005615	extracellular space	JCHAIN	IDA		Human	PMID:23398317
Cellular Component	GO:0005615	extracellular space	JCHAIN	HDA		Human	PMID:23580065
Cellular Component	GO:0071748	monomeric IgA immunoglobulin complex	JCHAIN	IDA		Human	PMID:23250751
Cellular Component	GO:0071756	pentameric IgM immunoglobulin complex	JCHAIN	IDA		Human	PMID:21786026
Cellular Component	GO:0071756	pentameric IgM immunoglobulin complex	JCHAIN	IDA		Human	PMID:23250751
Cellular Component	GO:0071756	pentameric IgM immunoglobulin complex	JCHAIN	IDA		Human	PMID:24145934
Cellular Component	GO:0071752	secretory dimeric IgA immunoglobulin complex	JCHAIN	IDA		Human	PMID:24145934
Cellular Component	GO:0071751	secretory IgA immunoglobulin complex	JCHAIN	IDA		Human	PMID:23250751
Cellular Component	GO:0071751	secretory IgA immunoglobulin complex	JCHAIN	IDA		Human	PMID:24145934
Cellular Component	GO:0071751	secretory IgA immunoglobulin complex	JCHAIN	IDA		Human	PMID:32029686
Biological Process	GO:0002250	adaptive immune response	JCHAIN	IDA		Human	PMID:21786026
Biological Process	GO:0019731	antibacterial humoral response	JCHAIN	IDA		Human	PMID:23250751
Biological Process	GO:0003094	glomerular filtration	JCHAIN	IMP		Human	PMID:23398317
Biological Process	GO:0045087	innate immune response	JCHAIN	IDA		Human	PMID:21786026
Biological Process	GO:0060267	positive regulation of respiratory burst	JCHAIN	IDA		Human	PMID:24145934
Biological Process	GO:0065003	protein-containing complex assembly	JCHAIN	IMP		Human	PMID:17237408
Biological Process	GO:0001895	retina homeostasis	JCHAIN	HEP		Human	PMID:23580065

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern